Results 31 to 40 of about 8,085,982 (176)

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]

PLoS ONE, 2014
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock, Qi Ma, Biju Issac, Enrique A Mesri   +3 more
doaj   +1 more source

Messenger RNA Sequence Rather than Protein Sequence Determines the Level of Self-synthesis and Antigen Presentation of the EBV-encoded Antigen, EBNA1 [PDF]

, 2012
peer-reviewedViruses establishing persistent latent infections have evolved various mechanisms to avoid immune surveillance. The Epstein-Barr virus-encoded nuclear antigen, EBNA1, expressed in all EBV-associated malignancies, modulates its own protein ...
David J Lynn, Judy T Tellam, Rajiv Khanna, David J. Lynn (107188), Lea Lekieffre, Lynn, David J, Khanna, Rajiv, Judy T. Tellam (107182), Zhong, Jie, Jie Zhong (39213), Tellam, Judy T, Jie Zhong, Rajiv Khanna (107190), Lea Lekieffre (107185), Lekieffre, Lea   +14 more
core   +1 more source

Modulation of immune system by Kaposi’s sarcoma-associated herpesvirus:Lessons from viral evasion strategies

Frontiers in Microbiology, 2012
Kaposi’s sarcoma-associated herpesvirus (KSHV), a member of the herpesvirus family, has evolved to establish a long-term, latent infection of cells such that while they carry the viral genome gene expression is highly restricted.
Hye-Ra eLee, Kevin eBrulois, LaiYee eWong, Jae U. eJung   +3 more
doaj   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus, the Etiological Agent of All Epidemiological Forms of Kaposi’s Sarcoma

, 2021
International audienceSimple SummaryKaposi’s sarcoma-associated herpesvirus (KSHV) is one of the seven oncogenic viruses currently recognized by the International Agency for Research on Cancer.
Adélie Gothland, Calvez, Vincent, Aude Jary, Valentin Leducq, Gothland, Adélie, Veyri, Marianne, Marianne Veyri, Anne-Geneviève Marcelin, Leducq, Valentin, Jary, Aude, Marcelin, Anne-Geneviève, Vincent Calvez   +11 more
core   +1 more source

The T-Cell Immune Response against Kaposi's Sarcoma-Associated Herpesvirus

Advances in Virology, 2010
Kaposi's sarcoma-associated herpesvirus (KSHV) is the aetiological agent of Kaposi's sarcoma (KS), the most frequently arising malignancy in individuals with untreated HIV/AIDS.
Rebecca C. Robey, Salvinia Mletzko, Frances M. Gotch   +2 more
doaj   +1 more source

Long Non-Coding RNA and Epigenetic Gene Regulation of KSHV

Viruses, 2014
Kaposi’s sarcoma-associated herpesvirus (KSHV/human herpesvirus 8) is a γ-herpesvirus linked to Kaposi’s sarcoma (KS) and two lymphoproliferative disorders, primary effusion lymphoma (PEL or body-cavity B-lymphoma [BCBL]) and a subset of Multicentric ...
Mel Campbell, Hsing-Jien Kung, Yoshihiro Izumiya   +2 more
doaj   +1 more source

Pseudomonas aeruginosa Stimulates Inflammation and Enhances Kaposi’s Sarcoma Herpesvirus-Induced Cell Proliferation and Cellular Transformation through both Lipopolysaccharide and Flagellin

mBio, 2020
Inflammation triggered by innate immunity promotes carcinogenesis in cancer. Kaposi’s sarcoma (KS), a hyperproliferative and inflammatory tumor caused by Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, is the most common cancer in AIDS patients.
Ashley Markazi, Paige M. Bracci, Michael McGrath, Shou-Jiang Gao   +3 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Owen, Christopher B, Hughes, DJ, Berndt, Anja, Schumann, Sophie, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Baquero-Perez, Belinda, Jackson, Brian R, Berndt, A, Owen, CB, Hughes, David J, Baquero-Perez, B, Schumann, S   +13 more
core   +1 more source

Seroprevalence of antibodies against Kaposi's sarcoma-associated herpesvirus among HIV-negative people in China

Infectious Agents and Cancer, 2017
Background Little information on the prevalence of Kaposi’s sarcoma associated herpesvirus (KSHV) among HIV-negative individuals is available from Asia.
Tiejun Zhang, Zhenqiu Liu, Jun Wang, Veenu Minhas, Charles Wood, Gary M. Clifford, Na He, Silvia Franceschi   +7 more
doaj   +1 more source