Results 51 to 60 of about 8,085,982 (176)

Genipin Enhances Kaposi's Sarcoma-Associated Herpesvirus Genome Maintenance. [PDF]

PLoS ONE, 2016
Kaposi's sarcoma-associated herpesvirus (KSHV) is a Gammaherpesvirus that causes acute infection and establishes life-long latency. KSHV causes several human cancers, including Kaposi's sarcoma, an acquired immune deficiency syndrome (AIDS)-related form ...
Miyeon Cho, Seok Won Jung, Soomin Lee, Kuwon Son, Gyu Hwan Park, Jong-Wha Jung, Yu Su Shin, Taegun Seo, Hyosun Cho, Hyojeung Kang   +9 more
doaj   +1 more source

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

HIV Medicine, EarlyView.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart, R. Palich, M. Veyri, S. Bregigeon‐Ronot, M.‐C. Picot, C. Vidal, L. Galicier, S. Choquet, J.‐P. Spano, M.‐A. Valantin, A. Makinson   +10 more
wiley   +1 more source

Targeted therapy for Kaposi??s sarcoma and Kaposi??s sarcoma-associated herpesvirus [PDF]

, 2007
To summarize major recent findings on the biology of human herpesvirus-8, i.e. Kaposi’s sarcoma-associated herpesvirus, and the implications of these findings for Kaposi’s sarcoma ...
Dittmer, Dirk P, Krown, Susan E
core   +1 more source

ORFeome-based arrays in eukaryotic expression vectors - a new approach to screen for the function of viral proteins [PDF]

, 2005
Since its first description in 1994 by Yuan Chang and Patrick Moore, Kaposi’s sarcoma-associated herpesvirus (KSHV) or Human Herpesvirus 8 (HHV-8) has emerged as a pathogen of international public health importance.
Roupelieva, Maria
core   +1 more source

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Latency

Frontiers in Microbiology, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus that infects humans and exhibits a biphasic life cycle consisting of latent and lytic phases.
Mel Campbell, Wan-Shan Yang, Wayne W. Yeh, Chen-Hsuan Kao, Pei-Ching Chang   +4 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]

, 2003
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
Sitas, F., Hale, M., Newton, R., Urban, MI, Wojcicki, J.M., Martin Hale, Bourboulia, D., Newton, R, Bourboulia, D, Wojcicki, JM, Rob Newton, Hale, M, Stein, L., Patel, M, Moosa Patel, Ranjan Sur, Sur, R., Stein, L, Margaret I Urban, Sur, R, Ruff, P, Ruff, P., Lara Stein, Sitas, F ; https://orcid.org/, Janet M Wojcicki, Freddy Sitas, Patel, M., Paul Ruff, Dimitra Bourboulia, Urban, M.I.   +29 more
core   +2 more sources

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

Transplant Infectious Disease, EarlyView.
Among 135 cases of post‐liver transplant HHV8 disease (4 from NSW), presentations varied, and mortality was high (44%). Donor screening was rare, and donor‐derived infection was suspected in 33%. Survival improved with mTORi, reduced immunosuppression, chemotherapy, and, for non‐KS disease, donor screening. ABSTRACT Background Human herpesvirus 8 (HHV8)
Karen M. J. Waller, Sudarshan Arvind, Simone I. Strasser, Ken Liu, Geoff W. McCaughan, David G. Bowen, Madeleine Gill, Rebecca Davis, William Rawlinson, Sacha Stelzer‐Braid, Geoff Watson, Vinay Vanguru, Tina Marinelli   +12 more
wiley   +1 more source

Cells of the Innate and Adaptive Immune Systems in Kaposi’s Sarcoma

Journal of Immunology Research, 2020
Kaposi’s sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent is the Kaposi’s sarcoma-associated herpesvirus (KSHV). KS is the most prevalent malignancy among HIV-infected individuals globally and is considered an AIDS ...
Owen Ngalamika, Sody Munsaka
doaj   +1 more source