Results 61 to 70 of about 8,714,646 (173)
Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain
Since its discovery in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with lymphoproliferative disorders, particularly in patients infected with human ...
Jason R. Andrews +4 more
doaj +1 more source
HIV-negative disseminated Kaposi’s sarcoma in a Taiwanese patient
Kaposi’s sarcoma is a common malignancy associated with HIV/AIDS. Herein, we describe the case of a 26-year-old man who presented with bilateral neck and inguinal lymphadenopathy, a massive tumor on the gum, and a nodule over the left eye.
Chiung-Tang Huang +4 more
doaj +1 more source
Genipin Enhances Kaposi's Sarcoma-Associated Herpesvirus Genome Maintenance. [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) is a Gammaherpesvirus that causes acute infection and establishes life-long latency. KSHV causes several human cancers, including Kaposi's sarcoma, an acquired immune deficiency syndrome (AIDS)-related form ...
Miyeon Cho +9 more
doaj +1 more source
ABSTRACT Sub‐Saharan Africa (SSA) faces a unique cancer burden, characterized by a disproportionately high mortality‐to‐incidence ratio, a large share of infection‐related cancers, and distinct environmental exposures. Implementation of national policies on primary prevention is limited, and public literacy regarding cancer risk and curability remains ...
Anthony Kityo +14 more
wiley +1 more source
Modulation of oncogenic signaling networks by Kaposi’s sarcoma-associated herpesvirus
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of three human malignancies: Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. To persist and replicate within host cells, KSHV encodes proteins that
Jason P. Wong, Blossom Damania
core +1 more source
Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi +14 more
wiley +1 more source
Immune evasion by Kaposi’s sarcoma-associated herpesvirus
Persistent viral infections are often associated with serious diseases, primarily by altering functions of the host immune system. The hallmark of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection is the establishment of a life-long persistent ...
Parkash Gill +4 more
core +1 more source
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li +9 more
wiley +1 more source
An integrated computational and in vitro approach was used to investigate the anticancer activity of empagliflozin (EMPA) in A549 and HOP‐92 lung cancer cells and its interaction with hydroxychloroquine (HCQ). Network pharmacology identified 239 shared EMPA–lung cancer targets, while molecular docking predicted favorable interactions with ANXA8, SQSTM1/
Ola A. El‐Feky +6 more
wiley +1 more source
Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Owen, Christopher B +14 more
core +1 more source

