Results 81 to 90 of about 8,085,982 (176)

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Modulation of oncogenic signaling networks by Kaposi’s sarcoma-associated herpesvirus

, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of three human malignancies: Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. To persist and replicate within host cells, KSHV encodes proteins that
Jason P. Wong, Blossom Damania
core   +1 more source

Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency

PLoS Pathogens, 2022
Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr (EBV) are gammaherpesviruses associated with multiple human malignancies. KSHV is the etiological agent of Kaposi’s Sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s ...
Huirong Zhang, Jason P. Wong, Guoxin Ni, Patricio Cano, Dirk P. Dittmer, Blossom Damania   +5 more
doaj  

Epidemiology and Transmission of Kaposi’s Sarcoma-Associated Herpesvirus

Viruses, 2014
This review summarizes the current knowledge pertaining to Kaposi sarcoma-associated herpesvirus (KSHV) epidemiology and transmission. Since the identification of KSHV twenty years ago, it is now known to be associated with Kaposi’s sarcoma (KS ...
Veenu Minhas, Charles Wood
doaj   +1 more source

Kaposi’s Sarcoma Herpesvirus Genome Persistence [PDF]

, 2016
Kaposi’s sarcoma-associated herpesvirus (KSHV) has an etiologic role in Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman’s disease. These diseases are most common in immunocompromised individuals, especially those with AIDS. Similar
Kaye, Kenneth, Shijun Li, Kenneth M. Kaye, Franceline Juillard, Li, Shijun, Min Tan, Juillard, Franceline, Tan, Min   +7 more
core   +1 more source

Exploitation of Cellular Cytoskeletons and Signaling Pathways for Cell Entry by Kaposi’s Sarcoma-Associated Herpesvirus and the Closely Related Rhesus Rhadinovirus

Pathogens, 2012
As obligate intracellular pathogens, viruses depend on the host cell machinery to complete their life cycle. Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus causally linked to the development of Kaposi’s sarcoma and several other ...
Wei Zhang, Shou-Jiang Gao
doaj   +1 more source

Human Gammaherpesvirus 8 Oncogenes Associated with Kaposi’s Sarcoma

, 2022
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human gammaherpesvirus 8 (HHV-8), contains oncogenes and proteins that modulate various cellular functions, including proliferation, differentiation, survival, and apoptosis, and is integral ...
Marinho, Pedro do Nascimento, Vanessa Salete de Paula, Pedro do Nascimento Marinho, de Paula, Vanessa Salete, Amanda de Oliveira Lopes, Lopes, Amanda de Oliveira, Letícia d’Ambrosio de Souza Medeiros, Medeiros, Letícia d’Ambrosio de Souza   +7 more
core   +1 more source

A gammaherpesviral internal repeat contributes to latency amplification. [PDF]

, 2007
Gammaherpesviruses cause important infections of humans, in particular in immunocompromised patients. The genomes of gammaherpesviruses contain variable numbers of internal repeats whose precise role for in vivo pathogenesis is not well understood.
Steer, Beatrix, Susanne El-Gogo, Andreas Waha, Adler, Heiko, El-Gogo, Susanne, Thakur, Nagendra N., Freimüller, Klaus, Waha, Andreas, Heiko Adler, Nagendra N Thakur, Beatrix Steer, Klaus Freimüller   +11 more
core   +2 more sources

Pan‐gammaherpesvirus control via a broadly neutralising gB antibody

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Zi‐Ying Jiang, Peng‐Lin Li, Chu Xie, Cong Sun   +3 more
wiley   +1 more source

Co-infections and Pathogenesis of KSHV-Associated Malignancies

Frontiers in Microbiology, 2016
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpes virus 8 (HHV-8) is one of the several carcinogenic viruses that infect humans.
Suhani eThakker, Subhash C Verma
doaj   +1 more source