Results 71 to 80 of about 8,714,646 (173)
Kaposi’s Sarcoma-Associated Herpesvirus ORF7 Is Essential for Virus Production
Kaposi’s sarcoma-associated herpesvirus (KSHV) causes Kaposi’s sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman disease. Although capsid formation and maturation in the alpha-herpesvirus herpes simplex virus 1 are well understood ...
Masahiro Fujimuro +4 more
core +1 more source
Determining the Role of Kaposi’s Sarcoma-associated Herpesvirus LANA Protein in the Development of Persistent Infection [PDF]
Kaposi’s Sarcoma-associated Herpesvirus (KSHV) is a human cancer virus that causes Kaposis’ sarcoma, the most common cancer found in AIDS patients. Our lab is working to develop humanized mice as a novel animal model to study KSHV infection and related ...
Gardiner, Jamie, Berges, Dr. Brad
core
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source
Asymptomatic Violaceous Papules of the Penis in a Patient With HIV
JEADV Clinical Practice, EarlyView.
Jhon Edwin Rodríguez‐Vásquez +5 more
wiley +1 more source
Potato virus Y (PVY) coat protein (CP) interacts with cytosolic phosphoglucomutase (cPGM) in the cytosol, redirecting carbohydrate flux towards respiratory and pentose phosphate pathways. Consequently, the plant cell can meet the increased ATP, NADPH and biosynthetic precursor requirements for viral RNA synthesis, thereby promoting PVY accumulation and
Prabu Gnanasekaran +2 more
wiley +1 more source
Overview on Epstein–Barr Virus–Host Interactions With a Focus on Host Cell Transcriptome Alterations
ABSTRACT The Epstein–Barr virus (EBV) belongs to the gamma subgroup of human herpesviruses. EBV is particularly lymphotropic regarding its latency, meaning that it preferentially targets lymphocytes as its immunological niche. During the establishment of the complex virus–host relationships, the virus influences the human host cell transcriptome ...
Louise Wallot +5 more
wiley +1 more source
Human Gammaherpesvirus 8 Oncogenes Associated with Kaposi’s Sarcoma
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human gammaherpesvirus 8 (HHV-8), contains oncogenes and proteins that modulate various cellular functions, including proliferation, differentiation, survival, and apoptosis, and is integral ...
Marinho, Pedro do Nascimento +7 more
core +1 more source
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang +8 more
wiley +1 more source
Glutamine Metabolism in Health and Diseases
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding +3 more
wiley +1 more source
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart +10 more
wiley +1 more source

