Results 71 to 80 of about 13,850 (184)
KSHV and Human Diseases: Beyond KS, PEL and MCD
MicroorganismsKaposi’s Sarcoma-associated herpesvirus (KSHV) has been etiologically linked to several human cancers, including Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). However, recent studies suggest that KSHV
Caroline Grace Firmin +2 more
doaj +1 more source
Novel Virus Related to Kaposi’s Sarcoma–Associated Herpesvirus from Colobus Monkey
Emerging Infectious Diseases, 2019 We determined the complete genome sequence of a virus isolated from a mantled guereza that died of primary effusion lymphoma. The virus is closely related to Kaposi’s sarcoma–associated herpesvirus (KSHV) but lacks some genes implicated in KSHV ...
Akshay Dhingra +9 more
doaj +1 more source
Kaposi's sarcoma-associated herpesvirus open reading frame 50 represses p53-induced transcriptional activity and apoptosis [PDF]
, 2001 Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 50 (ORF50) encodes a viral transcriptional activator which stimulates the transcription of viral early and late genes of KSHV.
Gwack, YOUSANG +6 more
core +1 more source
PLoS ONE, 2014 Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically associated with Kaposi's sarcoma (KS), the most common AIDS-related malignancy. KSHV vIL-6 promotes KS development, but the exact mechanisms remain unclear. Here, we reported that KSHV vIL-6
Jing Wu +7 more
doaj +1 more source
The Role of DNA Viruses in Human Cancer
Cancer Informatics, 2023 This review discusses the possible involvement of infections-associated cancers in humans, with virus infections contributing 15% to 20% of total cancer cases in humans.
Mehdi Fazlalipour +3 more
doaj +1 more source
Protein chainmail variants in dsDNA viruses. [PDF]
, 2015 First discovered in bacteriophage HK97, biological chainmail is a highly stable system formed by concatenated protein rings. Each subunit of the ring contains the HK97-like fold, which is characterized by its submarine-like shape with a 5-stranded β ...
Chiou, Joshua, Zhou, Z Hong
core +2 more sources
Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer
MedComm, Volume 7, Issue 4, April 2026.This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin +10 more
wiley +1 more source
Interactions between KSHV ORF57 and the novel human TREX proteins, CHTOP and CIP29 [PDF]
, 2016 The coupling of mRNA processing steps is essential for precise and efficient gene expression. The human transcription/export (hTREX) complex is a highly conserved multi-protein complex responsible for eukaryotic mRNA stability and nuclear export. We have
Baquero-Perez, B +2 more
core +1 more source
HIV Medicine, Volume 27, Issue 4, Page 498-512, April 2026.Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre +2 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.ABSTRACT Cornus officinalis (CO) is a traditional herbal medicine renowned in Traditional Chinese Medicine (TCM) for its properties of tonifying the liver and kidney and replenishing vital essence. Meanwhile, wine‐processed CO (pCO) exhibits superior pharmacological effects, including anti‐inflammatory, antioxidant and anti‐fibrotic activities. However,
Yongsheng Fu +4 more
wiley +1 more source