Results 41 to 50 of about 18,080 (165)

Kaposi’s sarcoma-associated herpesvirus infection promotes proliferation of SH-SY5Y cells by the Notch signaling pathway

Cancer Cell International, 2021
Background The cancer caused by Kaposi’s sarcoma-associated herpesvirus (KSHV) infection is one of the major causes of death in AIDS patients. Some patients have neurological symptoms, which appear to be associated with KSHV infection, based on the ...
Dongdong Cao, Shuyuan Wu, Xiaolu Wang, Ying Li, Huiling Xu, Zemin Pan, Zhaofu Wu, Lei Yang, Xiaohua Tan, Dongmei Li   +9 more
doaj   +1 more source

Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency. [PDF]

PLoS Pathogens, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the host following an acute infection. Reactivation from latency contributes to the development of KSHV-induced malignancies, which include Kaposi's sarcoma (KS), the most ...
Fengchun Ye, Fuchun Zhou, Roble G Bedolla, Tiffany Jones, Xiufen Lei, Tao Kang, Moraima Guadalupe, Shou-Jiang Gao   +7 more
doaj   +1 more source

Characteristics of circulating KSHV-infected viroblasts during active KSHV(+) multicentric Castleman disease

, 2022
Kaposi sarcoma–associated herpesvirus (KSHV)/human herpesvirus 8–associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder that mainly occurs in immunocompromised hosts.
Chbihi, Marwa, Latour, Sylvain, Sylvain Latour, Guislaine Carcelain, Dossier, Antoine, Villemonteix, Juliette, Vanjak, Anthony, Rémi Bertinchamp, Boutboul, David, Knapp, Silene, Sbihi, Zineb, Le Goff, Jerome, Lionel Galicier, Edouard Flamarion, Zineb Sbihi, Marwa Chbihi, Marc-Antoine Silvestrini, Eric Oksenhendler, Carcelain, Guislaine, Garzaro, Margaux, Justine Poirot, Margaux Garzaro, Anthony Vanjak, Silvestrini, Marc-Antoine, Charles Cassius, Galicier, Lionel, Anne Marie Ronchetti, Oksenhendler, Eric, Martin de Frémont, Gregoire, Silene Knapp, Juliette Villemonteix, Véronique Meignin, Antoine Dossier, Ronchetti, Anne Marie, Gregoire Martin de Frémont, David Boutboul, Jerome Le Goff, Maud Salmona, Benjamin Fournier, Flamarion, Edouard, Lebbé, Celeste, Celeste Lebbé, Bertinchamp, Rémi, Fournier, Benjamin, Meignin, Véronique, Salmona, Maud, Cassius, Charles, Poirot, Justine   +47 more
core   +1 more source

Molecular detection and genotyping of human herpes virus 8 in blood donors in Congo

Вопросы вирусологии
Objectives. Human herpesvirus 8 (HHV8) is rarely studied in Congo, despite its prevalence in Africa. Among healthy individuals, HHV-8 does not always lead to a life-threatening infection; however, in immunocompromised individuals, it could lead to more ...
Patrina Joseph Iloukou, Anicet Luc Magloire Boumba, Dorine Florence Luthera Ngombe, Norvi Rigobert Bienvenu Massengo, Gervillien Arnold Malonga, Donatien Moukassa, Moulay Mustapha Ennaji   +6 more
doaj   +1 more source

HLA polymorphisms and detection of kaposi sarcoma-associated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study

Infectious Agents and Cancer, 2010
Kaposi sarcoma-associated herpesvirus (KSHV, also called Human herpesvirus 8 or HHV8) is a γ-2 herpesvirus that causes Kaposi sarcoma. KSHV seroprevalence rates vary geographically with variable rates recorded in different sub Sahara African countries ...
Figueiredo Constança, Bhatia Kishor, Bakaki Paul M, Owor Anchilla M, Ndugwa Christopher M, Schulz Thomas F, Pfeiffer Ruth M, Verboom Murielle, Guech-Ongey Mercy, Eiz-Vesper Britta, Blasczyk Rainer, Mbulaiteye Sam M   +11 more
doaj   +1 more source

A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy

Signal Transduction and Targeted Therapy, 2023
Dilated cardiomyopathy (DCM) is the leading cause of heart transplantation. By microRNA (miRNA) array, a Kaposi’s sarcoma-associated herpes virus (KSHV)-encoded miRNA, kshv-miR-K12-1-5p, was detected in patients with DCM.
Yanru Zhao, Huaping Li, Hengzhi Du, Zhongwei Yin, Mengying He, Jiahui Fan, Xiang Nie, Yang Sun, Huiying Hou, Beibei Dai, Xudong Zhang, Yuanyuan Cai, Kunying Jin, Nan Ding, Zheng Wen, Jiang Chang, Chen Chen, Dao Wen Wang   +17 more
doaj   +1 more source

Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1.

PLoS Biology, 2016
Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi's sarcoma, encodes 25 mature viral miRNAs. MCP-1-induced protein-1 (MCPIP1), a critical regulator of immune homeostasis, has been shown to suppress miRNA biosynthesis via ...
Christine Happel, Dhivya Ramalingam, Joseph M Ziegelbauer   +2 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi, Hiroko Kuwabara, Hiroko Nakayama, Mayo Odaka, Kozue Ariga, Isako Kataoka, Mari Tomiuka, Mayumi Uragami, Chihiro Deguchi, Shizuka Ono, Reika Takeda, Yoshitaka Kurisu, Yoshinobu Hirose, Yuuki Kinoshita, Taiji Yokote   +14 more
wiley   +1 more source

KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation

, 2019
Kaposi’s sarcoma associated herpesvirus (KSHV), like all herpesviruses maintains lifelong persistence with its host genome in latently infected cells with only a small fraction of cells showing signatures of productive lytic replication.
Jianxin You (121729), Yan Yuan (20767), Yan Yuan, Erle S. Robertson (7340108), Zachary L Lamplugh, Paul Lieberman, Fengchao Lang (5205029), Rajnish Kumar Singh, Jianxin You, Erle S Robertson, Paul Lieberman (7340105), Fengchao Lang, Zachary L. Lamplugh (6180686), Rajnish Kumar Singh (5205032)   +13 more
core   +1 more source