Results 41 to 50 of about 22,605 (225)

Selected genes of Human herpesvirus-8 associated Kaposi's sarcoma among patients with Human Immunodeficiency Virus-1 and Acquired Immunodeficiency Disease Syndrome

The Pan African Medical Journal, 2019
INTRODUCTION: Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients.
Rodgers Norman Demba, Nathan Shaviya, Sylviah Mweyeli Aradi, Walter Mwanda   +3 more
doaj   +1 more source

Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. [PDF]

, 2020
Molecular mechanisms of Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation have been studied primarily by measuring the total or average activity of an infected cell population, which often consists of a mixture of both nonresponding and ...
Campbell, Mel, Chuang, Frank, Guevara-Plunkett, Sara, Izumiya, Chie, Izumiya, Yoshihiro, Kumar, Ashish, Luxardi, Guillaume, Lyu, Yuanzhi, Nakajima, Ken-Ichi, Soulika, Athena, Wang, Kang-Hsin   +10 more
core  

Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. [PDF]

, 2013
The establishment of latency is an essential step for the life-long persistent infection and pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV).
Brulois, Kevin, Izumiya, Yoshihiro, Jung, Jae U, Kung, Hsing-Jien, Lee, Hye-Ra, Tepper, Clifford, Toth, Zsolt   +6 more
core   +3 more sources

Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity

Angewandte Chemie, EarlyView.
Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim, Sandra Liebscher, Rasmus Klintrot, Lorenzo Vallino, Marcelo Masman, Andreas H. Simon, Marianne Hahn, Sven Hennig, Saskia Neubacher, Frank Bordusa, Tom N. Grossmann   +10 more
wiley   +2 more sources

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.

PLoS Pathogens, 2017
Kaposi sarcoma-associated herpesvirus (KSHV) causes several tumors and hyperproliferative disorders. Hypoxia and hypoxia-inducible factors (HIFs) activate latent and lytic KSHV genes, and several KSHV proteins increase the cellular levels of HIF.
Coralie Viollet, David A Davis, Shewit S Tekeste, Martin Reczko, Joseph M Ziegelbauer, Francesco Pezzella, Jiannis Ragoussis, Robert Yarchoan   +7 more
doaj   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System

Pathogens, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer.
Seung-Min Yoo, Myung-Shin Lee
doaj   +1 more source

Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia. [PDF]

PLoS Pathogens, 2018
Kaposi's sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes.
Rajnish Kumar Singh, Fengchao Lang, Yonggang Pei, Hem Chandra Jha, Erle S Robertson   +4 more
doaj   +1 more source

Quantitative Analysis of Kaposi Sarcoma–Associated Herpesvirus (KSHV) in KSHV‐Associated Diseases [PDF]

The Journal of Infectious Diseases, 2006
Accurate numbers of copies of Kaposi sarcoma-associated herpesvirus (KSHV) and numbers of virus-infected cells in lesions caused by KSHV-associated diseases are unknown.Quantitative polymerase chain reaction (PCR) and computerized imaging of immunohistochemical analysis were performed on pathologic sections of samples from persons with KSHV-associated ...
Yasuko, Asahi-Ozaki, Yuko, Sato, Takayuki, Kanno, Tetsutaro, Sata, Harutaka, Katano   +4 more
openaire   +2 more sources

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV–MCD) and the KSHV Inflammatory Cytokine Syndrome

Frontiers in Microbiology, 2012
Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was appreciated that this virus was associated with most cases of multicentric Castleman disease (MCD) arising in patients infected with human immunodeficiency virus.
Mark N. Polizzotto, Thomas S. Uldrick, Duosha Hu, Robert Yarchoan   +3 more
doaj   +1 more source

Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]

, 2012
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark, Gazzard, Brian G, Goodier, Martin R, Gregson, John NS, Kuri-Cervantes, Leticia, Mela, Christopher M   +5 more
core   +1 more source