Results 41 to 50 of about 17,773 (204)

Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South Africa

Infectious Agents and Cancer, 2011
Background Kaposi sarcoma (KS) is the most common AIDS-defining tumour in HIV-infected individuals in Africa. Kaposi sarcoma herpes virus (KSHV) infection precedes development of KS.
Maskew Mhairi, MacPhail A, Whitby Denise, Egger Matthias, Wallis Carole L, Fox Matthew P   +5 more
doaj   +1 more source

Application of the CDK9 inhibitor FIT-039 for the treatment of KSHV-associated malignancy

BMC Cancer, 2023
Chronic infection with Kaposi’s sarcoma-associated herpes virus (KSHV) in B lymphocytes causes primary effusion lymphoma (PEL), the most aggressive form of KSHV-related cancer, which is resistant to conventional chemotherapy.
Tetsunori Sakamoto, Masahiko Ajiro, Akira Watanabe, Shingo Matsushima, Keiji Ueda, Masatoshi Hagiwara   +5 more
doaj   +1 more source

Selected genes of Human herpesvirus-8 associated Kaposi's sarcoma among patients with Human Immunodeficiency Virus-1 and Acquired Immunodeficiency Disease Syndrome

The Pan African Medical Journal, 2019
INTRODUCTION: Kaposi's sarcoma (KS) is a kind of cancer that causes flat or raised lesions containing Human herpes virus 8 (HHV8). The KS lesions are common among immunosuppressed HIV patients.
Rodgers Norman Demba, Nathan Shaviya, Sylviah Mweyeli Aradi, Walter Mwanda   +3 more
doaj   +1 more source

Seroprevalence and risk factors for Kaposi’s Sarcoma associated herpesvirus among men who have sex with men in Shanghai, China

BMC Infectious Diseases, 2023
Background This study aimed to facilitate the understanding of the transmission route and risk factors that might contribute to the infection of Kaposi’s sarcoma associated herpesvirus (KSHV) among men who have sex with men (MSM).
Yi Li, Xingcan Zhang, Yue Zhang, Minqi Wei, Sijie Tao, Ying Yang   +5 more
doaj   +1 more source

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.

PLoS Pathogens, 2017
Kaposi sarcoma-associated herpesvirus (KSHV) causes several tumors and hyperproliferative disorders. Hypoxia and hypoxia-inducible factors (HIFs) activate latent and lytic KSHV genes, and several KSHV proteins increase the cellular levels of HIF.
Coralie Viollet, David A Davis, Shewit S Tekeste, Martin Reczko, Joseph M Ziegelbauer, Francesco Pezzella, Jiannis Ragoussis, Robert Yarchoan   +7 more
doaj   +1 more source

Prevalence and correlates of Kaposi’s sarcoma-associated herpesvirus and herpes simplex virus type 2 infections among adults: evidence from the NHANES III data

Virology Journal, 2022
Background Kaposi’s sarcoma-associated herpes virus (KSHV) prevalence and risk factors exhibit considerable variations across populations in different geographic regions. Determinants and the transmission routes of KSHV infection are uncertain.
Xin Zhang, Yiyun Xu, Yi Li, Huangbo Yuan, Zhenqiu Liu, Tiejun Zhang   +5 more
doaj   +1 more source

Quantitative Analysis of Kaposi Sarcoma–Associated Herpesvirus (KSHV) in KSHV‐Associated Diseases [PDF]

The Journal of Infectious Diseases, 2006
Accurate numbers of copies of Kaposi sarcoma-associated herpesvirus (KSHV) and numbers of virus-infected cells in lesions caused by KSHV-associated diseases are unknown.Quantitative polymerase chain reaction (PCR) and computerized imaging of immunohistochemical analysis were performed on pathologic sections of samples from persons with KSHV-associated ...
Yasuko, Asahi-Ozaki, Yuko, Sato, Takayuki, Kanno, Tetsutaro, Sata, Harutaka, Katano   +4 more
openaire   +2 more sources

Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency. [PDF]

PLoS Pathogens, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes a latent infection in the host following an acute infection. Reactivation from latency contributes to the development of KSHV-induced malignancies, which include Kaposi's sarcoma (KS), the most ...
Fengchun Ye, Fuchun Zhou, Roble G Bedolla, Tiffany Jones, Xiufen Lei, Tao Kang, Moraima Guadalupe, Shou-Jiang Gao   +7 more
doaj   +1 more source

Analysis of the Expression Pattern of microRNA of KSHV in KSHV-infected Human Cells [PDF]

Journal of Bacteriology and Virology, 2013
Kaposi"s sarcoma associated herpesvirus (KSHV) is subdivided into gamma-herpesvirus and causes Kaposi"s sarcoma in human immunodeficiency virus (HIV)-infected patients. A defining feature of herpesviral biology is the presence of two alternative genetic lifestyles - a latent infection and a lytic replicative cycle.
Sil Kim, Jaehyuk Jang, Myung-Shin Lee, Seung-Min Yoo   +3 more
openaire   +1 more source

A Kaposi’s sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy

Signal Transduction and Targeted Therapy, 2023
Dilated cardiomyopathy (DCM) is the leading cause of heart transplantation. By microRNA (miRNA) array, a Kaposi’s sarcoma-associated herpes virus (KSHV)-encoded miRNA, kshv-miR-K12-1-5p, was detected in patients with DCM.
Yanru Zhao, Huaping Li, Hengzhi Du, Zhongwei Yin, Mengying He, Jiahui Fan, Xiang Nie, Yang Sun, Huiying Hou, Beibei Dai, Xudong Zhang, Yuanyuan Cai, Kunying Jin, Nan Ding, Zheng Wen, Jiang Chang, Chen Chen, Dao Wen Wang   +17 more
doaj   +1 more source