Seroprevalence of Kaposi sarcoma-associated herpesvirus and other serologic markers in the Brazilian Amazon. [PDF]
, 2009 To determine the presence of Kaposi sarcoma-associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Mascheretti, Melissa +27 more
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Frontiers in Microbiology, 2021 Kaposi’s sarcoma-associated herpesvirus (KSHV) is an etiologic agent of Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman disease. In studies of KSHV, efficient virus production and isolation are essential.
Su-Kyung Kang +5 more
doaj +1 more source
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin [PDF]
, 2010 Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu ...
Wilson, Sam J. +48 more
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KSHV-LANA breadth and magnitude compared between EnKS, EpKS, and HIV-/HIV+ asymptomatic individuals.
, 2022 The number of reactive peptides and their magnitudes per individual was calculated and compared across disease states, in each group, and across each region within LANA, respectively.
Sydney J. Bennett (10232183) +6 more
core +1 more source
KSHV/HHV8‐associated lymphomas [PDF]
British Journal of Haematology, 2007 SummaryThis review looks at the current state of knowledge on primary effusion lymphoma (PEL) and other Kaposi sarcoma herpesvirus (KSHV)/human herpesvirus 8 (HHV8)‐associated lymphomas. In 1995, KSHV DNA sequences were identified within a distinct subgroup of acquired immunodeficiency syndrome‐related non‐Hodgkin lymphomas localized in body cavities ...
Antonino, Carbone, Annunziata, Gloghini
openaire +2 more sources
AIDS and Non AIDS-Related Malignant Lymphoma in Tanzania. [PDF]
, 2006 Malignant lymphoma (ML) in HIV patients, are second in frequency to Kaposi's sarcoma (AKS) as AIDS-defining tumors. In Africa the frequency of AIDS-related lymphoma (ARL) is rare and the findings are controversial.
Ekman, Marianne +25 more
core +1 more source
High-throughput sequencing analysis of a "hit and run" cell and animal model of KSHV tumorigenesis.
PLoS Pathogens, 2020 Kaposi's sarcoma (KS), is an AIDS-associated neoplasm caused by the KS herpesvirus (KSHV/ HHV-8). KSHV-induced sarcomagenesis is the consequence of oncogenic viral gene expression as well as host genetic and epigenetic alterations. Although KSHV is found
Julian Naipauer +7 more
doaj +1 more source
Kaposi’s Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System
Pathogens, 2020 Kaposi’s sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer.
Seung-Min Yoo, Myung-Shin Lee
doaj +1 more source
Metabolic reprogramming of Kaposi's sarcoma associated herpes virus infected B-cells in hypoxia. [PDF]
PLoS Pathogens, 2018 Kaposi's sarcoma associated herpesvirus (KSHV) infection stabilizes hypoxia inducible factors (HIFs). The interaction between KSHV encoded factors and HIFs plays a critical role in KSHV latency, reactivation and associated disease phenotypes.
Rajnish Kumar Singh +4 more
doaj +1 more source
Latently KSHV-Infected Cells Promote Further Establishment of Latency upon Superinfection with KSHV [PDF]
International Journal of Molecular Sciences, 2021 Kaposi’s sarcoma-associated herpesvirus (KSHV) is a cancer-related virus which engages in two forms of infection: latent and lytic. Latent infection allows the virus to establish long-term persistent infection, whereas the lytic cycle is needed for the maintenance of the viral reservoir and for virus spread.
Chen Gam ze Letova +3 more
openaire +2 more sources