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Oral EBV and KSHV Infection in HIV
Advances in Dental Research, 2006The gamma herpesviruses, Kaposi’s-sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), are tightly associated with the development of AIDS-associated oral disease and malignancy during immune suppression. The objective of this investigation was to characterize oral infection and pathogenesis in healthy and immune-suppressed individuals ...
J, Webster-Cyriaque +3 more
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Journal of Medical Virology, 2012
AbstractEpstein–Barr virus (EBV) establishes lifelong latency in B‐lymphocytes following infection. Although in immune‐competent individuals EBV remains in a quiescent state, in immunodeficient individuals, such as those with AIDS or transplant recipients, B‐lymphocytes infected with EBV proliferate to give rise to lymphoproliferative diseases ...
Koichi Ricardo, Katsumura +2 more
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AbstractEpstein–Barr virus (EBV) establishes lifelong latency in B‐lymphocytes following infection. Although in immune‐competent individuals EBV remains in a quiescent state, in immunodeficient individuals, such as those with AIDS or transplant recipients, B‐lymphocytes infected with EBV proliferate to give rise to lymphoproliferative diseases ...
Koichi Ricardo, Katsumura +2 more
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Role of EBERs in the Pathogenesis of EBV Infection
2010Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) are noncoding RNAs that are expressed abundantly in latently EBV-infected cells. Previous studies demonstrated that EBERs (EBER1 and EBER2) play significant roles in various EBV-infected cancer cells. EBERs are responsible for malignant phenotypes of Burkitt's lymphoma (BL) cells including resistance ...
Dai, Iwakiri, Kenzo, Takada
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Neuropilin 1 Is an Entry Factor That Promotes EBV Infection of Nasopharyngeal Epithelial Cells [PDF]
Epstein–Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal epithelial cells remain elusive.
Wanli Liu, Yi-Xin Zeng, Guo-Kai Feng
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Therapeutic potential of EBV infection
Science Signaling, 2020Targeting MYC or factors that sustain its expression may turn EBV infection into a therapeutic tool for B cell lymphomas.
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Circulating Interferon in EBV Infections
1987Interferon (IFN) is known to be synthesized in viral infections as an important defense mechanism (1). Our data report IFN determination in two groups of patients: one group with acute infections (influenza, enterovirus infections), and another group with different expressions of EBV infections [primary infection, “active infection” and nasopharyngeal ...
J. Icart +4 more
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Journal de Pédiatrie et de Puériculture, 1992
Le virus isole par Epstein et Barr (EBV) en 1964 dans les prelevements de lymphome de Burkitt doit son actualite a un certain nombre de donnees nouvelles: -il est authentifie avec certitude comme l'agent de la mononucleose infectieuse, maladie jusque-la soupconnee sur des donnees cliniques pauci-symptomatiques et des criteres biologiques non ...
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Le virus isole par Epstein et Barr (EBV) en 1964 dans les prelevements de lymphome de Burkitt doit son actualite a un certain nombre de donnees nouvelles: -il est authentifie avec certitude comme l'agent de la mononucleose infectieuse, maladie jusque-la soupconnee sur des donnees cliniques pauci-symptomatiques et des criteres biologiques non ...
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EBV infection drives MS pathology: Yes
Multiple Sclerosis JournalAfter two decades of dedicated studies, in 2022, Ascherio and colleagues have provided the most definitive and compelling evidence that Epstein–Barr virus (EBV) is an early and essential factor in MS development. Now, the crux of MS research is to find out how a ubiquitous, generally asymptomatic infection interacts with genetic and environmental ...
Aloisi, Francesca, Salvetti, Marco
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Cellular Immunity in EBV Infections
1985Effective study of cellular immunity to EBV had to wait for developments in basic cellular immunology. Once a high level of definition was achieved in this area, particularly in T cell markers, the recognition of the NK system, and the vital role of lymphokines, the stage was set for progress.
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