Results 21 to 30 of about 1,782,169 (280)

Chromatin Control of EBV Infection and Latency. [PDF]

Curr Top Microbiol Immunol
Epstein-Barr Virus (EBV) establishes latent infection as a circular, chromatinized episome that can persist in the nucleus of dividing and quiescent B cells, as well as in some NK, T, and epithelial cancer cells. During latency, the viral genome can express a diverse program of viral genes that have profound effects on the host cell, including capacity
Lieberman PM, Tempera I.
europepmc   +4 more sources

Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling

Biomedical Journal, 2022
T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj   +1 more source

Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation

Life Science Alliance, 2023
The CTP nucleotide is essential for cell proliferation. This study explores the respective contributions of CTP synthetases 1 and 2 in cell proliferation.
Norbert Minet, Anne-Claire Boschat, Rebecca Lane, David Laughton, Philip Beer, Hélène Asnagli, Claire Soudais, Tim Bourne, Alain Fischer, Emmanuel Martin, Sylvain Latour   +10 more
doaj   +1 more source

Strategies of Epstein-Barr virus to evade innate antiviral immunity of its human host

Frontiers in Microbiology, 2022
Epstein-Barr virus (EBV) is a double-stranded DNA virus of the Herpesviridae family. This virus preferentially infects human primary B cells and persists in the human B cell compartment for a lifetime.
Manuel Albanese, Manuel Albanese, Manuel Albanese, Manuel Albanese, Takanobu Tagawa, Takanobu Tagawa, Takanobu Tagawa, Wolfgang Hammerschmidt, Wolfgang Hammerschmidt   +8 more
doaj   +1 more source

R9AP Is a Common Receptor for EBV Infection in Epithelial Cells and B Cells [PDF]

Nature
Ping Han, Song Gao, Erle S Robertson
exaly   +2 more sources

EBV infection drives MS pathology: No. [PDF]

Mult Scler
't Hart BA, van Luijn MM.
europepmc   +3 more sources

A primary nasopharyngeal three-dimensional air-liquid interface cell culture model of the pseudostratified epithelium reveals differential donor- and cell type-specific susceptibility to Epstein-Barr virus infection.

PLoS Pathogens, 2021
Epstein-Barr virus (EBV) is a ubiquitous γ-herpesvirus with latent and lytic cycles. EBV replicates in the stratified epithelium but the nasopharynx is also composed of pseudostratified epithelium with distinct cell types.
Phillip Ziegler, Yarong Tian, Yulong Bai, Sanna Abrahamsson, Alan Bäckerholm, Alex S Reznik, Anthony Green, John A Moore, Stella E Lee, Michael M Myerburg, Hyun Jung Park, Ka-Wei Tang, Kathy Ho Yen Shair   +12 more
doaj   +1 more source

Valganciclovir is not associated with decreased EBV infection rate in pediatric kidney transplantation

Frontiers in Pediatrics, 2023
IntroductionPrimary infection or reactivation of Epstein-Barr Virus (EBV) is a significant cause of morbidity and mortality in pediatric kidney transplantation.
Elodie Cheyssac, Hamidou Savadogo, Nathan Lagoutte, Véronique Baudouin, Marina Charbit, Robert Novo, Anne-Laure Sellier-Leclerc, Marc Fila, Stéphane Decramer, Elodie Merieau, Ariane Zaloszyc, Jérôme Harambat, Gwenaelle Roussey   +12 more
doaj   +1 more source

Prevalence of Epstein-Barr Viral DNA among children at a single hospital in Suzhou, China

Jornal de Pediatria, 2022
Objective: This study aimed to describe the prevalence of Epstein-Barr virus (EBV)-DNA among children in Suzhou, and to explore the association between plasma EBV load and disease diagnosis.
Ting Shi, Linlin Huang, Jianmei Tian
doaj   +1 more source

In vitro Studies and Clinical Observations Imply a Synergistic Effect Between Epstein-Barr Virus and Dengue Virus Infection

Frontiers in Microbiology, 2021
Dengue virus (DENV) infection can lead to a complex spectrum of clinical outcomes, ranging from asymptomatic infection to life-threatening severe dengue. The reasons for thus drastically varying manifestations of the disease remain an enigma.
Xiao-Mei Deng, Ling-Zhai Zhao, Xue-Ying Liang, Dan Li, Lei Yu, Fu-Chun Zhang, Hua Zhang, Zhong-Yu Liu, Pei Xu   +8 more
doaj   +1 more source