Results 31 to 40 of about 21,931 (240)

Problems of reliability of electronic components

Modern Electronic Materials, 2015
This paper describes the problem of increasing the reliability of electronic components (EC) used for the fabrication of high-tech products. Two main ways of solving the problem are considered based on analysis of published data.
Vyacheslav A. Kharchenko
doaj   +1 more source

Online Model-Based Fault Detection of Synchronous Generators Using Residual Analysis

IEEE Access, 2021
In this paper, an online model-based fault detection approach based on residual analysis in synchronous generators (SGs) is presented. Two types of faults are studied in this paper: (i) reduction of the cross-sectional area of windings wires in SGs, and (
Zahra Masoumi, Bijan Moaveni, Sayed Mohammad Mousavi Gazafrudi, Jawad Faiz   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Altered Pallidocortical Low-Beta Oscillations During Self-Initiated Movements in Parkinson Disease

Frontiers in Systems Neuroscience, 2020
BackgroundParkinson disease (PD) patients have difficulty with self-initiated (SI) movements, presumably related to basal ganglia thalamocortical (BGTC) circuit dysfunction, while showing less impairment with externally cued (EC) movements.ObjectivesWe ...
Jeong Woo Choi, Mahsa Malekmohammadi, Hiro Sparks, Alon Kashanian, Katy A. Cross, Yvette Bordelon, Nader Pouratian, Nader Pouratian, Nader Pouratian   +8 more
doaj   +1 more source

Modulation of entorhinal cortex–hippocampus connectivity and recognition memory following electroacupuncture on 3×Tg-AD model: Evidence from multimodal MRI and electrophysiological recordings

Frontiers in Neuroscience, 2022
Memory loss and aberrant neuronal network activity are part of the earliest hallmarks of Alzheimer’s disease (AD). Electroacupuncture (EA) has been recognized as a cognitive stimulation for its effects on memory disorder, but whether different brain ...
Bingbing Lin, Lanlan Zhang, Xiaolong Yin, Xiaolong Yin, Xiaocheng Chen, Chendong Ruan, Tiecheng Wu, Zhizhen Liu, Jia Huang   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exercise and neural circuit stability in early Alzheimer’s disease: evidence across memory, executive, cholinergic, and circadian systems

Frontiers in Aging Neuroscience
Early Alzheimer’s disease (AD) is increasingly understood as a phase in which neural circuit dysfunction emerges alongside molecular pathology and local neuronal injury.
Qing Li, Mingchen Gu, Wei Li
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source