Results 121 to 130 of about 389,890 (305)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Considerations regarding the impulse ignition test for level of protection “eb” and ignition test for protection levels “eb” and “ec” stator insulation systems of Ex-proof electric motors

MATEC Web of Conferences
According to the provisions of the 5th edition of the standard IEC 60079 – 7, equipment protection by increased safety “e”, for Level of protection “eb” and “ec” electrical machines, if the rated voltage exceeds 1 kV, type tests in explosive mixtures have to be carried out, in order to certify such an electrical machine. The purpose of this paper is to
Magyari Mihai, Moldovan Lucian, Rad Marcel   +2 more
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo [PDF]

, 1991
Trunk neural crest cells and motor axons move in a segmental fashion through the rostral (anterior) half of each somitic sclerotome, avoiding the caudal (posterior) half.
Bronner-Fraser, Marianne, Ranscht, Barbara   +1 more
core  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Highly Reproducible Automated Tip Coater for In Situ and Operando EC-STM Measurements

Surfaces
High-quality, reproducible tip coatings are essential for minimizing faradaic currents in electrochemical scanning tunneling microscopy (EC-STM), especially during in situ and operando measurements.
Robert Kurczak, Paulina Wira, Anna Futyma, Radosław Wasielewski, Tomasz Kosmala   +4 more
doaj   +1 more source

Characterization and source apportionment of atmospheric organic and elemental carbon during fall and winter of 2003 in Xi'an, China [PDF]

Atmospheric Chemistry and Physics, 2005
Continuous measurements of atmospheric organic and elemental carbon (OC and EC) were taken during the high-pollution fall and winter seasons at Xi'an, Shaanxi Province, China from September 2003 through February 2004. Battery-powered mini-volume samplers
J. J. Cao, F. Wu, F. Wu, J. C. Chow, S. C. Lee, Y. Li, S. W. Chen, Z. S. An, K. K. Fung, J. G. Watson, C. S. Zhu, S. X. Liu   +11 more
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Phase change material in automated window shades [PDF]

, 2013
The purpose of this report is to detail the development process for a phase change material window shading system, which stores solar thermal energy and later releases it indoors to provide nighttime space heating.
Adler, Quinlan, Gallau, Jake, Nash, Ali, Zatopa, Alexander   +3 more
core   +1 more source