Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu +7 more
wiley +1 more source
Impact of early versus delayed cord clamping on oxidative stress in neonates with intrauterine growth restriction: a prospective randomized controlled trial. [PDF]
Demir MB +3 more
europepmc +1 more source
Abstract figure legend A 10 week time‐restricted feeding (TRF) regimen was implemented in aged female mice following 12 weeks of high‐fat diet (HFD) feeding. TRF partially reversed HFD‐induced weight and fat mass gain, reduced adipocyte size and increased size heterogeneity in white adipose tissue.
Theresa Bushman +2 more
wiley +1 more source
Simulated endocardial vegetation model highlights the complexity of high-inoculum infections among β-lactamase-producing organisms. [PDF]
Fratoni AJ.
europepmc +1 more source
Retrospective analysis of cervical screening abnormalities in women with type 3 transformation zone without visible lesions. [PDF]
Yang J +5 more
europepmc +1 more source
Spatio‐Temporal Diversity of Calcium Activity in Microglia
Ca2+ activity mostly occurs in microglial processes and stays localized. When it spreads, it often shows a directional bias and is constrained by branch points. Activity strongly relies on P2Y12 receptors and is shaped by neuronal activity. ABSTRACT Microglia, the brain's innate immune cells, possess complex, highly motile branched processes. These act
Hiroshi Horiuchi +3 more
wiley +1 more source
Perspectives from Hysterectomy Specimens on the Hidden Malignancy Risk in HSIL Patients with Surgical Margin Continuity. [PDF]
Görgülü G, Sanci M.
europepmc +1 more source
What's new? Cervical cancer screening is challenging in postmenopausal women, partly due to physiological changes that reduce the sensitivity of cytology and colposcopy. This study evaluated the diagnostic performance of combined PAX1 and JAM3 gene methylation testing in a large cohort of postmenopausal women undergoing colposcopy. Compared to cytology
Huanzi Peng +11 more
wiley +1 more source
Life cycle assessment of eco-friendly high performance cementitious composites incorporating construction and industrial waste. [PDF]
Mehmood M +4 more
europepmc +1 more source

