Results 61 to 70 of about 7,008 (268)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Complete solution to a conjecture of Zhang-Liu-Zhou [PDF]
Transactions on Combinatorics, 2014 Let dn;m = 2n+1 and En;m be the graph obtained from a path Pdn;m+1 = v0v1:::vdn;m by joining each vertex of Kn by joining each vertex of Kn. Zhang, Liu and Zhou [On the maximal eccentric connectivity indices of graphs, Appl. Math. J.
Mostafa Tavakoli +3 more
doaj
Computing the Ediz eccentric connectivity index of discrete dynamic structures
Open Physics, 2017 From the earlier studies in physical and chemical sciences, it is found that the physico-chemical characteristics of chemical compounds are internally connected with their molecular structures. As a theoretical basis, it provides a new way of thinking by
Wu Hualong +4 more
doaj +1 more source
On the Randi\'{c} index and conditional parameters of a graph [PDF]
, 2013 The aim of this paper is to study some parameters of simple graphs related with the degree of the vertices. So, our main tool is the $n\times n$ matrix ${\cal A}$ whose ($i,j$)-entry is $$ a_{ij}= \left\lbrace \begin{array}{ll} \frac{1}{\sqrt{\delta_i ...
Rodríguez, J. A., Sigarreta, J. M.
core
The magnetic reversal in dot arrays recognized by the self-organized adaptive neural network
, 2003 The remagnetization dynamics of monolayer dot array superlattice XY 2-D spin model with dipole-dipole interactions is simulated. Within the proposed model of array, the square dots are described by the spatially modulated exchange-couplings.
Bauer +23 more
core +1 more source
Eccentric Connectivity Index of Chemical Trees
, 2011 14 pages, 2 ...
c, Aleksandar Ili\', Gutman, Ivan
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
VERTEX-ECCENTRICITY DESCRIPTORS IN DENDRIMERS
Studia Universitatis Babes-Bolyai Chemia, 2017 In this paper, we present graph theoretical methods to compute several vertex-eccentricity-based molecular descriptors such as the eccentric connectivity index, total eccentricity, average eccentricity and first and second Zagreb eccentricity indices ...
Mahdieh AZARI +2 more
doaj +1 more source