Results 71 to 80 of about 7,534 (257)

Resistance Training with Co-ingestion of Anti-inflammatory Drugs Attenuates Mitochondrial Function

Frontiers in Physiology, 2017
Aim: The current study aimed to examine the effects of resistance exercise with concomitant consumption of high vs. low daily doses of non-steroidal anti-inflammatory drugs (NSAIDs) on mitochondrial oxidative phosphorylation in skeletal muscle.
Daniele A. Cardinale, Daniele A. Cardinale, Mats Lilja, Mirko Mandić, Thomas Gustafsson, Filip J. Larsen, Tommy R. Lundberg   +6 more
doaj   +1 more source

Chemical Maturation Controls Bioavailability of Fetuin‐A‐Mineral Complexes in Biomineralization

Advanced Functional Materials, EarlyView.
The role of Fetuin‐A‐mineral complexes in matrix mineralization is unclear. Here, Fetuin‐A‐mineral complexes were found to exist in functionally distinct states that determine mineral bioavailability: chemically labile calciprotein monomers directly mineralize collagen fibrils, while chemically matured primary calciprotein particles require cellular ...
Judith M. Schaart, Luco Rutten, Shaina V. To, Alisha A. Shah, Martijn Martens, Elena Macías‐Sánchez, Willi Jahnen‐Dechent, Nico Sommerdijk, Anat Akiva   +8 more
wiley   +1 more source

Neuro-Mechanical Analysis of Eccentric Overload of Elbow Flexors [PDF]

, 2013
Eccentric overload in training settings utilizes loads higher than concentric one repetition maximum (1RM). There is no clear definition of eccentric “failure” or 1RM using conventional weights, so eccentric 1RM is estimated to be between 145-190 ...
Leal, Frederico
core  

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Eccentric overload training in patients with chronic Achilles tendinopathy: a systematic review

, 2020
Background: Eccentric overload training seems to be a promising conservative intervention in patients with chronic Achilles tendinopathy. The efficacy of eccentric overload training on the outcome measures of pain and physical functioning are not exactly
R De Knikker, H M Wittink, J J Kingma
core  

miR-210 overexpression increases pressure overload-induced cardiac fibrosis

Non-coding RNA Research
Aortic stenosis, a common valvular heart disease, can lead to left ventricular pressure overload, triggering pro-fibrotic responses in the heart. miR-210 is a microRNA that responds to hypoxia and ischemia and plays a role in immune regulation and in ...
G. Zaccagnini, D. Baci, S. Tastsoglou, I. Cozza, A. Madè, C. Voellenkle, M. Nicoletti, C. Ruatti, M. Longo, L. Perani, C. Gaetano, A. Esposito, F. Martelli   +12 more
doaj   +1 more source

Does handball throwing velocity increase after an eccentric overload-induced postactivation potentiation?

European Journal of Human Movement, 2020
Introduction: Post-activation performance enhancement (PAPE) has been defined as an increase in performance of voluntary movements after a high-intensity voluntary task. This phenomenon can be achieved through different strategies. However, the relationship between a conditioning eccentric overload (EO) exercise and PAPE in the upper extremities is ...
Pablo Asencio, Rafael Sabido, Adrián García-Valverde, Jose Luis Hernández-Davó   +3 more
openaire   +3 more sources

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source