Results 61 to 70 of about 31,283 (265)
Advanced Robotics Research, EarlyView.This review maps the methods to monitor robots’ health by fusing vibration, sound, control signals, vision, force, and oil information with artificial intelligence. It identifies deep learning, transfer learning, digital twins, and physics‐informed models as key methodological pathways enabling earlier diagnosis, safer human–robot collaboration, and ...
Yuting Qiao +6 more
wiley +1 more source
Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing
Advanced Science, EarlyView.Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan +13 more
wiley +1 more source
Nanopore‐Based Protein Deceleration and Sensing Using Graphene/Si3N4 Dual Membrane Cavity
Advanced Science, EarlyView.A graphene/Si3N4 dual membrane cavity system achieves multi‐stage protein deceleration through spatial geometry. Multi‐level current traces provide high‐resolution spatial localization and early warning signals. ABSTRACT Sequencing of protein with nanopores has emerged as a powerful tool offering rapid readout, high accuracy, low cost, and portability.
Yubin Cao, Junzhou He, Wei Si
wiley +1 more source
Degree-Distance Based Topological Indices of Crystal Cubic Carbon Structure
Atoms, 2018 Chemical graph theory comprehends the basic properties of an atomic graph. The sub-atomic diagrams are the graphs that are comprised of particles called vertices and the covalent bond between them are called edges.
Hong Yang +3 more
doaj +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
Experimental and Numerical Analysis for Eccentricity Solution in Double-Layer Space Truss
BuildingsThis paper shows an extensive study on the Typical Connections used in Double-Layer Space Truss. For this structural system, the ends of the bars are flattened to connect the bars. However, the flattening process results in a highly plastic stamping zone
Welington Vital +5 more
doaj +1 more source
Advanced Science, EarlyView.A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen +15 more
wiley +1 more source
Advanced Science, EarlyView.Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu +8 more
wiley +1 more source
Advanced Science, EarlyView.A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang +12 more
wiley +1 more source
Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG
Advanced Science, EarlyView.Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan +10 more
wiley +1 more source