Development of an insilico model of eccrine sweat using molecular modelling techniques [PDF]
Scientific Reports, 2022 Eccrine sweat is an ideal surrogate diagnostic biofluid for physiological and metabolic biomarkers for wearable biosensor design. Its periodic and non-invasive availability for candidate analytes such as glucose and cortisol along with limited ...
Parijat Deshpande +4 more
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The protease corin regulates electrolyte homeostasis in eccrine sweat glands. [PDF]
PLoS Biology, 2021 Sweating is a basic skin function in body temperature control. In sweat glands, salt excretion and reabsorption are regulated to avoid electrolyte imbalance. To date, the mechanism underlying such regulation is not fully understood.
Meiling He +13 more
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Physiological mechanisms determining eccrine sweat composition [PDF]
European Journal of Applied Physiology, 2020 AbstractPurposeThe purpose of this paper is to review the physiological mechanisms determining eccrine sweat composition to assess the utility of sweat as a proxy for blood or as a potential biomarker of human health or nutritional/physiological status.MethodsThis narrative review includes the major sweat electrolytes (sodium, chloride, and potassium),
Lindsay B. Baker, Anthony S. Wolfe
semanticscholar +5 more sources
Eccrine sweat gland development and sweat secretion [PDF]
Experimental Dermatology, 2015 AbstractEccrine sweat glands help to maintain homoeostasis, primarily by stabilizing body temperature. Derived from embryonic ectoderm, millions of eccrine glands are distributed across human skin and secrete litres of sweat per day. Their easy accessibility has facilitated the start of analyses of their development and function.
Chang-Yi Cui, David Schlessinger
semanticscholar +5 more sources
Eccrine Sweat as a Biofluid for Profiling Immune Biomarkers [PDF]
PROTEOMICS – Clinical Applications, 2018 PurposeSweat is a relatively unexplored biofluid for diagnosis and monitoring of disease states. In this study, the proteomic profiling of immune‐related biomarkers from healthy individuals are presented.Experimental DesignEccrine sweat samples are collected from 50 healthy individuals. LC‐MS/MS is performed on two pools of sweat samples from five male
Jennifer Blain Christen +3 more
semanticscholar +5 more sources
Cholinergic- rather than adrenergic-induced sweating play a role in developing and developed rat eccrine sweat glands [PDF]
Exp Anim, 2020 Both cholinergic and adrenergic stimulation can induce sweat secretion in human eccrine sweat glands, but whether cholinergic and adrenergic stimulation play same roles in rat eccrine sweat glands is still controversial.
Lei Zhang +4 more
semanticscholar +2 more sources
Integrated Transcriptomic and Proteomic Analysis of Human Eccrine Sweat Glands Identifies Missing and Novel Proteins* [PDF]
Mol Cell Proteomics, 2019 This study reports the first in-depth RNA and protein expression profiles of human sweat glands. RNA-sequencing and proteomic analysis were performed on ∼250 sweat glands collected from a healthy individual.
C. Na +7 more
semanticscholar +2 more sources
Quantification of cortisol in human eccrine sweat by liquid chromatography - tandem mass spectrometry. [PDF]
Analyst, 2016 Cortisol has long been recognized as the "stress biomarker" in evaluating stress related disorders. Plasma, urine or saliva are the current source for cortisol analysis.
Min Jia +4 more
semanticscholar +2 more sources
Differential Innervation of Secretory Coils and Ducts in Human Eccrine Sweat Glands [PDF]
Chinese Medical Journal, 2018 Background: Previous studies demonstrate that eccrine sweat glands are innervated by both cholinergic and adrenergic nerves. However, it is still unknown whether the secretory coils and ducts of eccrine sweat glands are equally innervated by the ...
Zhan Ouyang +4 more
doaj +2 more sources
Soft, skin-mounted microfluidic systems for measuring secretory fluidic pressures generated at the surface of the skin by eccrine sweat glands. [PDF]
Lab Chip, 2017 During periods of activity, sweat glands produce pressures associated with osmotic effects to drive liquid to the surface of the skin. The magnitudes of these pressures may provide insights into physiological health, the intensity of physical exertion ...
Jungil Choi +9 more
semanticscholar +2 more sources