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Nonsteroidal Ecdysone Agonists
2005Nonsteroidal ecdysone agonists are novel compounds that have become attractive candidates not only as pest control agents in agriculture but also as tools for research. Their narrow spectrum of activity makes them relatively safe as pesticides, and their mode of action as ligands for gene expression has found application in gene therapy and inducing ...
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ECDYSONE AND ECDYSONE-ANALOGUES: THEIR ASSAY AND ACTION ON DIAPAUSING PUPAE OF THE CYNTHIA SILKWORM
The Biological Bulletin, 19681. Six ecdysones of plant origin are compared with synthetic α-ecdysone in terms of their ability to provoke normal or abnormal development of diapausing pupae and isolated pupal abdomens of the cynthia silkworm (Samia cynthia).2. The activity of the seven materials ranks in the following order: cyasterone > ponasterone B > ponasterone A > ponasterone ...
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Ecdysone receptors and their biological actions
2000Publisher Summary This chapter discusses the ecdysone receptors and their biological actions. It also summarizes the insect endocrinology and the roles of these steroids in the molting and metamorphosis. Natural hormones that lead to molting and metamorphosis are ecdysones.
L M, Riddiford, P, Cherbas, J W, Truman
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Ecdysone-controlled expression of transgenes
Expert Opinion on Biological Therapy, 2002Inducible expression systems show great potential for use in human gene therapy and systems based on insect ecdysone receptors are particularly promising candidates. This article describes such systems and reviews actual and potential uses of ecdysone-controlled transgenes in vitro and in vivo.
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New players in the regulation of ecdysone biosynthesis
Journal of Genetics and Genomics, 2008Xun Huang, James T Warren
exaly