Results 41 to 50 of about 21,212 (213)

Most Sinorhizobium meliloti Extracytoplasmic Function Sigma Factors Control Accessory Functions

mSphere, 2018
Bacteria must sense alterations in their environment and respond with changes in function and/or structure in order to cope. Extracytoplasmic function sigma factors (ECF σs) modulate transcription in response to cellular and environmental signals.
Claus Lang, Melanie J. Barnett, Robert F. Fisher, Lucinda S. Smith, Michelle E. Diodati, Sharon R. Long   +5 more
doaj   +1 more source

The integrated Lei‐CNS PBPK‐PD model effectively predicts clozapine brain disposition and D2 receptor occupancy in humans

British Journal of Clinical Pharmacology, EarlyView.
Aim Clozapine, used for treatment‐resistant schizophrenia, has a narrow therapeutic window and highly variable plasma pharmacokinetics (PK), necessitating careful monitoring. Direct measurement of unbound brain PK in humans is unethical. To develop a physiologically based pharmacokinetic–pharmacodynamic (PBPK‐PD) model to predict clozapine brain ...
Mengxu Zhang, Thomas I. F. H. Cremers, Vivi Rottschäfer, Elizabeth C. M. de Lange   +3 more
wiley   +1 more source

‘In a small school, it's just capacity all of the time’: Delivery and experiences of a national early career teacher development initiative across diverse school settings in England

British Educational Research Journal, EarlyView.
Abstract Effective early career support is associated with a variety of professional and personal benefits for teachers and their schools. However, research indicates that the contextual features of schools, such as their size and geographic location, influence the support that new teachers receive.
Ellen Turner, Alexandra Bates, David Aldridge, Roisin Ellison, Grace Healy, Jen Knowles, Katy Micklewright, Grace Stevens, Calum Davey   +8 more
wiley   +1 more source

Influence of interface bonding strength on brittle crack propagation in bi-material structural components [PDF]

, 2004
The influence of the interface bonding strength on brittle crack propagation in bi-material structures is investigated. In this study a crack is set at the vertex of the interface between two joined dissimilar materials.
M. PAGGI, CARPINTERI A, Paggi, M., Paggi, Marco, Carpinteri, Alberto, Carpinteri, A.   +5 more
core  

Electrochemical Fluorination of Partially Fluorinated Dialkylethers. Synthesis of Sevoflurane Derivatives (CF3)2CHOCHF2, (CF3)2CHOCF3, and (CF3)2CFOCF3

Chemistry – A European Journal, EarlyView.
Electrochemical fluorination (ECF, Simons process) is a valuable method for the fluorination of partially fluorinated dialkyl ethers, providing an inexpensive, scalable, and safe access to partially fluorinated ethers with a higher fluorine content and the perfluorinated analogues that are hardly accessible using other fluorination techniques ...
Tanja Knuplez, Leon N. Schneider, Erik R. Csapo, Peer Kirsch, Nikolai V. Ignat'ev, Maik Finze   +5 more
wiley   +1 more source

Prospective study of immunological factors in non-inflammatory bowel disease enterocutaneous fistulas

BMC Surgery, 2011
Background Enterocutaneous fistulas (ECF) are debilitating and usually result following complex abdominal surgery. While there is an association with inflammatory bowel disease (IBD), a large number of fistulas occur after surgery not related to IBD. The
Warusavitarne Janindra, Knight Stella C, Gabe Simon M, Ullah Mohammad R, Al-Hassi Hafid O, Hart Ailsa L, Rahbour Goher, Vaizey Carolynne J   +7 more
doaj   +1 more source

Adipose tissue-derived stem cells as a therapeutic strategy for enterocutaneous fistula: an experimental model study

Acta Cirúrgica Brasileira, 2023
Purpose: Enterocutaneous fistula (ECF) is a condition in which there is an abnormal connection between the intestinal tract and the skin. It can lead to high morbidity and mortality rates despite the availability of therapeutic options.
Vitor Penteado Figueiredo Pagotto, Cristina Pires Camargo, Paula Vitória Cáceres, Silvana Cereijido Altran, Rolf Gemperli   +4 more
doaj   +1 more source

Convergence and Residual Error Analysis of Unsteady MHD Stagnation Flow Over a Cylindrical Surface With Streamline and Isotherm Visualization

Energy Science &Engineering, EarlyView.
The novelty of the current study is that the unsteady MHD Cross nanofluid model is, for the first time, coupled with the melting heat transfer at the stagnation point over a horizontally extended cylinder in a Darcy–Forchheimer porous medium. This work connects complex rheological behaviors and phase‐change phenomena in a unique way, with the only ...
Fahad Maqbul Alamrani, Ebrahem A. Algehyne, Mounirah Areshi, Muhammad Bilal, Mustafa Bayram, Jihad Younis, Anwar Saeed   +6 more
wiley   +1 more source

Assessment of the Impact of Early Diagnosis and Early Treatment in the Integrated Control of East Coast Fever (ECF) Involving Acquired Immunity Induced by Natural Infection in Ankole Cattle

Pathogens, 2023
The integrated control of East Coast fever (ECF) by early diagnosis and treatment involving acquired immunity induced by natural infection in Ankole cattle was assessed.
Ann Nanteza, Zachary Nsadha, Julius Nsubuga, Stephen Oligo, Anne Kazibwe, Clare Terundaja, Enock Matovu, George William Lubega   +7 more
doaj   +1 more source

A multicenter analysis of 1364 elective/rescue cerclages in Brazil: Perinatal outcomes, complications, and the role of vaginal progesterone

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate perinatal outcomes in women undergoing cervical cerclage for prevention of preterm birth in Brazilian maternity hospitals. Methods This retrospective cohort study included 1364 women with singleton pregnancies who underwent elective or rescue cervical cerclage between December 2003 and November 2025.
Isabella C. Bragheto, Gabriela M. Pereira, Camila Mirandez, Marcelo Luis Nomura, Elton Carlos Ferreira, Rodolfo C. de Pacagnella, Evelyn Traina, Danilo B. Silva, Karayna Gil Fernandes, Julia Negro, Conrado M. Coutinho, Manuella R. Pereira, Janete Vettorazzi, Julia Hubner, Edson Vieira Cunha Filho, Ellen M. Arlindo, Aluana R. Parola, Pedro D. Correa, Renato Passini Junior, Renato T. Souza   +19 more
wiley   +1 more source