Results 11 to 20 of about 20,858 (254)

Echinococcus multilocularis and Echinococcus shiquicus in a small mammal community on the eastern Tibetan Plateau: host species composition, molecular prevalence, and epidemiological implications

Parasites & Vectors, 2018
Background The eastern part of the Tibetan Plateau is now recognized as an endemic region with the highest reported human infection rates in the world of human alveolar echinococcosis (AE) caused by Echinococcus multilocularis.
Xu Wang, Jiayu Liu, Qingqiu Zuo, Zhiqiang Mu, Xiaodong Weng, Xiaohui Sun, Junyao Wang, Belgees Boufana, Philip S. Craig, Patrick Giraudoux, Francis Raoul, Zhenghuan Wang   +11 more
doaj   +2 more sources

High PD-1 and CTLA-4 expression correlates with host immune suppression in patients and a mouse model infected with Echinococcus multilocularis [PDF]

Parasites & Vectors
Background Alveolar echinococcosis (AE), a fatal disease caused by Echinococcus multilocularis, often affects the liver, with tumor-like growth. However, the mechanism by which E. multilocularis evades host immune surveillance remains unclear. Methods We
Ting Sun, Yi Yang, Yiwen Qiu, Tao Wang, Ming Yang, Shu Shen, Wentao Wang   +6 more
doaj   +2 more sources

Annual assessment of <i>Echinococcus multilocularis</i> surveillance reports submitted in 2025 in the context of Commission Delegated Regulation (EU) 2018/772. [PDF]

EFSA J
Abstract This report comprises the 15th assessment of the Echinococcus multilocularis surveillance scientific reports, provided by Finland, Ireland, the United Kingdom (Northern Ireland) and Norway on their respective surveillance programmes. Every year since 2012, EFSA presents the assessment to the European Commission in which the sampling strategy ...
European Food Safety Authority (EFSA), Zancanaro G, Papaleo S.   +2 more
europepmc   +2 more sources

A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice

Frontiers in Immunology, 2023
Introduction The objective of this study is to construct a multi-epitope vaccine GILE containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) infection based on the dominant epitopes of E. multilocularis EMY162, LAP,
P. Zhou, Z. Zhou, Meiduo Huayu, Lei Wang, Lin Feng, Yang Xiao, Y. Dai, M. Xin, Feng Tang, Runle Li   +9 more
semanticscholar   +1 more source

Echinococcus multilocularis drives the polarization of macrophages by regulating the RhoA-MAPK signaling pathway and thus affects liver fibrosis

Bioengineered, 2022
Echinococcus multilocularis is a small parasite that causes alveolar echinococcosis. It primarily induces liver disorder, such as liver fibrosis and even liver cancer, which severely endangers human lives.
Shigui Chong, Gen Chen, Z. Dang, Fuqiu Niu, Linghui Zhang, Hui Ma, Yumin Zhao   +6 more
semanticscholar   +1 more source

The golden jackal (Canis aureus): A new host for Echinococcus multilocularis and Trichinella britovi in Switzerland.

Schweizer Archiv für Tierheilkunde, 2022
INTRODUCTION The golden jackal (Canis aureus) is a wild canid new to Switzerland. It is an officially monitored species and all deceased individuals are submitted for post-mortem examination to collect baseline health data.
C. Frey, W. Basso, S. Zürcher-Giovannini, I. Marti, S. Borel, S. Guthruf, D. Gliga, B. Lundström-Stadelmann, F. Origgi, M. Ryser-Degiorgis   +9 more
semanticscholar   +1 more source

Echinococcus multilocularis and Other Taeniid Metacestodes of Muskrats in Luxembourg: Prevalence, Risk Factors, Parasite Reproduction, and Genetic Diversity

Pathogens, 2022
Muskrats (Ondatra zibethicus) are competent intermediate hosts for Echinococcus multilocularis, are frequently infected with this zoonotic cestode, and have even been proposed as a target species to monitor endemicity levels of this parasite.
Matilde Martini, S. Dumendiak, A. Gagliardo, Francesco Ragazzini, Letizia La Rosa, D. Giunchi, F. Thielen, T. Romig, A. Massolo, M. Wassermann   +9 more
semanticscholar   +1 more source

Suppressive effect of pseudolaric acid B on Echinococcus multilocularis involving regulation of TGF-β1 signaling in vitro and in vivo

Frontiers in Microbiology, 2022
Echinococcus multilocularis, the causative agent of alveolar echinococcosis (AE), severely threats human health and livestock farming. The first line of chemotherapeutic drug for AE is albendazole, which limits rapid extension of E.
Haijun Gao, Lele Huo, X. Mo, Bingxin Jiang, Yanping Luo, Bin Xu, Jingzhong Li, Xingming Ma, T. Jing, Zheng Feng, Ting Zhang, Wei Hu   +11 more
semanticscholar   +1 more source

Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection

PLoS Neglected Tropical Diseases, 2022
Background Echinococcus multilocularis causes alveolar echinococcosis (AE), a rising zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to chemotherapy using benzimidazoles and surgical intervention, with frequent ...
Michael Weingartner, S. Stücheli, Fadi Jebbawi, B. Gottstein, G. Beldi, B. Lundström-Stadelmann, Junhua Wang, A. Odermatt   +7 more
semanticscholar   +1 more source

Echinococcus multilocularis protoscoleces enhance glycolysis to promote M2 Macrophages through PI3K/Akt/mTOR Signaling Pathway

Pathogens and Global Health, 2022
Alveolar Echinococcosis (AE) is a zoonotic parasitic disease caused by Echinococcus multilocularis, but its pathogenesis remains unclear. The primary objective of this study is to explore whether Echinococcus multilocularis protoscoleces (PSCs) regulate ...
Tao Zhang, YaoGang Zhang, Zihan Yang, Yuan Jiang, Li Sun, Dengliang Huang, M. Tian, Yinhong Shen, Junping Deng, J. Hou, Yanyan Ma   +10 more
semanticscholar   +1 more source