Results 151 to 160 of about 119,669 (279)

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao, Jing Zhou, Jing Wang, Si‐Nan Zhao, Zhan‐Sheng Zhao, Qian Wang, Ya‐Nan Xie, Wei Jiao   +7 more
wiley   +1 more source

VERTICAL VELOERGOMETRY AND TRANSOESOPHAGEAL STRESS ECHOCARDIOGRAPHY

Российский кардиологический журнал, 2011
Transoesophageal (TE) assess in stress echocardiography (EchoCG) enables us to overcome the principal limitation of the method – poor visualization quality in patients with “non-diagnostic windows”.
A. B. Trivozhenko
doaj  

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Cardiac resynchronization therapy and pulmonary artery banding in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block

Pediatric Investigation, EarlyView.
The combination of cardiac resynchronization therapy and pulmonary artery banding was associated with substantial improvement in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block. Most patients exhibited marked improvement in clinical status and ventricular function, along with a reduction in QRS ...
Min Zeng, Fan Yang, Quanlin Li, Kai Ma, Zheng Dou, Kunjing Pang, Xinjie Lin, Shoujun Li, Xu Wang   +8 more
wiley   +1 more source

Chinese guideline for the prevention and control of complications associated to umbilical venous catheterization in neonates (2025)

Pediatric Investigation, EarlyView.
ABSTRACT This guideline aims to standardize the prevention and management of complications related to umbilical venous catheterization (UVC). It addresses nine clinical questions, categorized into three sections: (1) questions concerning UVC‐related infection, (2) catheter position, and (3) UVC maintenance.
The Subspecialty Group of Neonatology, Chinese Pediatric Society, Chinese Medical Association, Prevention and Control of Healthcare Associated Infection Society, Chinese Maternal and Child Health Association, National Center for Children's Health, China, Beijing Children's Hospital, Capital Medical University   +8 more
wiley   +1 more source

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

Phytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao, Tao Xu, Chao Ye, Ke Zhang, Xinyu Heng, Shaohong Huang, Yan Chen, Yitong Guo, Shengyi Shao, Zhi Wen, Chenwen Shao, Xiang Lu, Ning Sun, Hai Yang   +13 more
wiley   +1 more source

Amentoflavone, a Preferentially TGF‐β Receptor 1 Inhibitor, Alleviates Cardiac Remodeling and Dysfunction Through Modulating the TGF‐β/Smad and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu, Chengcheng Zhao, Xiaoping Li, Xinyi Guo, Wenjie Tan, Lu Zhou, Ye Zhang, Jianli Zhang, Shuo Zheng, Chunyu Zeng, Gengze Wu   +10 more
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Impact of socioeconomic status and remoteness of residence on pregnancy outcome in major congenital heart disease: mediation analysis

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Increased remoteness of residence (RoR) and lower socioeconomic status (SES) negatively impact the rate and gestational age (GA) at the diagnosis of major congenital heart disease (mCHD). We examined the direct and indirect relationships of RoR from a tertiary fetal cardiology center and Chan SES index with the rate of termination of
S. Bennett, L. K. Hornberger, A. Kaur, D. Fruitman, L. G. Eckersley   +4 more
wiley   +1 more source

Feline blood donation via cephalic intravenous catheter: A novel method

Veterinary Record, EarlyView.
Abstract Background Feline jugular blood donation requires heavy sedation or a very compliant cat. Donation using an intravenous catheter requires less restraint and potentially decreases stress. Methods This was an observational study of feline blood donors at a veterinary hospital between February and June 2023.
Charlotte Russo, Karen Humm
wiley   +1 more source