Results 101 to 110 of about 1,226 (208)

Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A

Phytotherapy Research, EarlyView.
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen, Xinghong Zhou, Yanting You, Jieyu Chen, Baizhao Peng, Yijian Deng, Shuai Ji, Ying Yang, Xiaohu Chen, Huaxi Liu, Shuxuan Yang, Hiu Yee Kwan, Wen Jin, Lei Zhang, Yuegang Wang, Xiaoshan Zhao, Yanyan Liu   +16 more
wiley   +1 more source

Two-dimensional and Doppler echocardiographic findings of congenital coronary artery fistula

The Turkish Journal of Pediatrics, 1992
Three patients with coronary artery fistula confirmed by coronary angiography and surgery were studied using two-dimensional and Doppler echocardiography. Two of these patients had left coronary artery-right ventricle fistula.
S Ozkutlu, M Saraçlar, S Atalay, A Bilgiç, Y Yurdakul, S Ciçek   +5 more
doaj  

Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function

Phytotherapy Research, EarlyView.
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng, Mingyang He, Haiying Wu, Tianjie Zhang, Yuxia Jiang, Chuanwei Xin, Meiling Zhang, Jiaqi He, Lulu Zheng   +8 more
wiley   +1 more source

Fetal cardiac remodeling in second trimester in pregnancies with pre‐eclampsia and/or fetal growth restriction: deep‐learning‐based approach using population‐wide data

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Pre‐eclampsia (PE) and fetal growth restriction (FGR) have been shown to impact fetal cardiac remodeling in the third trimester and postnatally, with evidence to suggest that this leads to increased long‐term cardiovascular risk. This study aimed to examine fetal cardiac remodeling in pregnancies with PE and/or FGR during the second ...
C. A. Taksøe‐Vester, K. Mikolaj, O. B. Petersen, C. K. Ekelund, N. G. Vejlstrup, C. Vedel, A. N. Christensen, A. Feragen, M. Nielsen, M. G. Tolsgaard   +9 more
wiley   +1 more source

Anti‐desmoglein‐2 autoantibodies do not discriminate between UK boxer dogs with and without arrhythmogenic right ventricular cardiomyopathy

Veterinary Record, EarlyView.
Abstract Background Evidence regarding the diagnostic utility of serum anti‐desmoglein‐2 (DSG2) autoantibodies for arrhythmogenic right ventricular cardiomyopathy (ARVC) in boxer dogs is conflicting. Methods Prospective standardised evaluation of apparently healthy boxer dogs for ARVC was performed at three referral centres, including blood pressure ...
Chia‐Hsuan Chang, Claire Watson, Diptendu Chatterjee, Jade Ward, Kieran Borgeat, Hannah Hodgkiss‐Geere, Joanna Dukes‐McEwan, Robert Hamilton, Melanie J. Hezzell   +8 more
wiley   +1 more source

Three-dimensional echocardiography

Journal of Cardiothoracic and Vascular Anesthesia, 1997
openaire   +2 more sources

Data privacy model using blockchain reinforcement federated learning approach for scalable internet of medical things

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Internet of Medical Things (IoMT) has typical advancements in the healthcare sector with rapid potential proof for decentralised communication systems that have been applied for collecting and monitoring COVID‐19 patient data. Machine Learning algorithms typically use the risk score of each patient based on risk factors, which could help ...
Chandramohan Dhasaratha, Mohammad Kamrul Hasan, Shayla Islam, Shailesh Khapre, Salwani Abdullah, Taher M. Ghazal, Ahmed Ibrahim Alzahrani, Nasser Alalwan, Nguyen Vo, Md Akhtaruzzaman   +9 more
wiley   +1 more source

Foetal Cardiac Function in Early Labour and Intrapartum Outcomes: A Prospective Observational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess foetal myocardial deformation in normo‐oxygenated foetuses in early labour and its relationship with intrapartum outcomes. Design Single centre prospective study. Setting Referral tertiary maternity unit. Population Uncomplicated singleton term pregnancies in early labour.
Andrea Dall'Asta, Chiara Melito, Beatrice Valentini, Mariagrazia Capurso, Maria Teresa Baffa, Olga Patey, Basky Thilaganathan, Tullio Ghi   +7 more
wiley   +1 more source

Three Ventricular Assist Devices (True TriVAD) as Bridge to Durable Biventricular Support (BiVAD) in LVAD Patient With Severe Aortic Regurgitation

Artificial Organs, EarlyView.
An LVAD patient with severe aortic regurgitation (AR) developed right heart failure and multi‐organ dysfunction (MOD). tRVAD support caused LV overload and pulmonary edema. Impella 5.5 implantation successfully unloaded the LV and stabilized the patient, enabling durable RVAD implantation with surgical aortic valve replacement.
Nikolaos Cholevas, Felix Schoenrath, Nicolas Merke, Denis Fries, Marcus Mueller, Johanna Mulzer, Evgenij Potapov   +6 more
wiley   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source