Results 41 to 50 of about 426,683 (300)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Confined Electrochemiluminescence Generation at Ultra-High-Density Gold Microwell Electrodes
Frontiers in Chemistry, 2021 Electrochemiluminescence (ECL) imaging analysis based on the ultra-high-density microwell electrode array (UMEA) has been successfully used in biosensing and diagnostics, while the studies of ECL generation mechanisms with spatial resolution remain ...
Jialian Ding +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A pragmatic macroeconomic default risk adjustment in developing countries
South African Journal of Economic and Management SciencesBackground: The expected credit loss (ECL) framework of International Financial Reporting Standards Foundation (IFRS) 9 typically comprises three components: probability of default (PD), loss given default (LGD) and exposure at default (EAD). Among these,
Suben Moodley +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
ECL: a specification environment for system-level design [PDF]
Proceedings 1999 Design Automation Conference (Cat. No. 99CH36361), 1999 We propose a new specification environment for system-level design called ECL. It combines the Esterel and C languages to provide a more versatile means for specifying heterogeneous designs. It can be viewed as the addition to C of explicit constructs from Esterel for waiting, concurrency and pre-emption, and thus makes these operations easier to ...
Luciano Lavagno, Ellen Sentovich
openaire +1 more source
, 2021 Supplemental material, sj-pdf-2-ecl-10.1177_14687984211041389 for Trilingualism and reading difficulty in a third (school) language: A case study of an at-risk child in French immersion by Maria Claudia Petrescu and Rena Helms-Park in Journal of Early ...
Rena Helms-Park (10842639) +1 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Annali di Ca’ Foscari. Serie occidentale, 2022 This article provides a philological and linguistic commentary on impersonal βρέχει ‘it rains’, discussed in the Atticist lexicon Phryn. Ecl. 255.
openaire +1 more source
A cholesterol biosensor based on the NIR electrogenerated-chemiluminescence (ECL) of water-soluble CdSeTe/ZnS quantum dots [PDF]
, 2015 This contribution examines the application of near infra-red (NIR) quantum dot (QD) containing films for cholesterol detection. Water-soluble, 2-(dimethylamino)ethanthiol (DAET) protected 800 nm CdSeTe/ZnS core-shell QDs were prepared and incorporated ...
Bertoncello, Paolo +7 more
core +1 more source