Results 51 to 60 of about 426,683 (300)
Supplemental Material, sj-pdf-1-ecl-10.1177_14687984221093242 for How family needs informed an early literacy family reading program in multilingual and multicultural Miami-Dade County by Melissa Baralt, Shayl F Griffith, K Lori Hanson, Nicolas André ...
Melissa Baralt (2397025) +5 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Static and active tactile perception and touch anisotropy: aging and gender effect
Although the human finger is the interface used for the touch process, very few studies have used its properties to provide a description of tactile perception regarding age and gender effects.
A. Abdouni +3 more
doaj +1 more source
Framework-Enhanced Electrochemiluminescence in Biosensing
Electrochemiluminescence (ECL) has attracted increasing attention owing to its intrinsic advantages of high sensitivity, good stability, and low background.
Haomin Fu +5 more
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Ru(bpy)32+/TPA system is a tremendously important electrochemiluminescence (ECL) system. Its ECL properties depend significantly on the electrodes used.
Saima Parveen +8 more
doaj +1 more source
Supplemental material, sj-pdf-1-ecl-10.1177_14687984211041389 for Trilingualism and reading difficulty in a third (school) language: A case study of an at-risk child in French immersion by Maria Claudia Petrescu and Rena Helms-Park in Journal of Early ...
Rena Helms-Park (10842639) +1 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

