Results 101 to 110 of about 212,448 (296)

AGENCY PROBLEMS IN TROUBLED COMPANIES: A UK-ITALY COMPARISON.

, 2010
In this discussion I will try to understand if it is possible to talk about a distribution of power between constituencies and how it is, eventually, regulated the coexistence of a plurality of interests under the U.K.
Tomasi, Tania
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Transfer-matrix modeling of spectral reflectivity for monitoring reactive-ion etching processes [PDF]

APL Photonics
We apply the transfer matrix method (TMM) to model the evolution of light spectral reflectivity during reactive ion etching of SiGe heterostructures used in electro-absorption modulators.
A. P. Milenin, J. R. Vaskasi, D. Kazakov, Y. Shimura, I. G. Koo, F. Ferraro, K. Devriendt   +6 more
doaj   +1 more source

Linear range comparison between RSV ECL assays and a diagnostic RSV F/G ELISA.

, 2016
The assay control was used to illustrate the linear range of the four ECL assays and the diagnostic F/G ELISA. Linearity samples were prepared from the assay control and serially diluted before addition to the MSD or ELISA plates.
Vera Chio (2608636), Bandita Parhy (2608648), Marla Chu (2608654), Edward E. Walsh (836781), Bodrey Ro (707320), Ann R. Falsey (2589907), Shushil Machhi (2608651), C. Kathy Wang (477686), Nancy Ulbrandt (2608660), Ryan Yamagata (2608639), Marcia Carlson (2608657), Samuel Park (2608642), Hoyin Mok (2608645), Li Yu (81651), Fengrong Zuo (477687), Tansy Leonardson (2608633), Mark T. Esser (106136), Sarah V. Maifeld (2608630)   +17 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Modeling Math Growth Trajectory—An Application of Conventional Growth Curve Model and Growth Mixture Model to ECLS K-5 Data

Journal of Educational Issues, 2016
<p>To model students’ math growth trajectory, three conventional growth curve models and three growth mixture models are applied to the Early Childhood Longitudinal Study Kindergarten-Fifth grade (ECLS K-5) dataset in this study. The results of conventional growth curve model show gender differences on math IRT scores. When holding socio-economic
openaire   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source