Results 61 to 70 of about 308,092 (299)

Modeling Theories and Theorizing Models: an Attempted Replication of Miller-Cotto & Byrnes’ (2019) Comparison of Working Memory Models Using ECLS-K Data

open access: yesEducational Psychology Review, 2021
Working memory is an essential mechanism in the cognitive learning process. However, its definitions and mechanisms remain a topic of debate. Miller-Cotto and Byrnes (Journal of Educational Psychology, 112(5), 1074–1084, 2020) reported a comparison of three models of working memory to determine which best accounted for data obtained from a national US ...
David F. Feldon, Kaylee Litson
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Assessing the impact of IFRS 9’s Expected Credit Loss model on capital allocation in Jordanian banks [PDF]

open access: yesBanks and Bank Systems
This study investigates the empirical effects of implementing the Expected Credit Loss (ECL) model under IFRS 9 on capital budgeting decisions within the Jordanian banking sector.
Mohammad Fawzi Shubita   +4 more
doaj   +1 more source

Deep Learning-Based Security Verification for a Random Number Generator Using White Chaos

open access: yesEntropy, 2020
In this paper, a deep learning (DL)-based predictive analysis is proposed to analyze the security of a non-deterministic random number generator (NRNG) using white chaos.
Cai Li   +6 more
doaj   +1 more source

Gaia eclipsing binary and multiple systems. Two-Gaussian models applied to OGLE-III eclipsing binary light curves in the Large Magellanic Cloud

open access: yes, 2017
The advent of large scale multi-epoch surveys raises the need for automated light curve (LC) processing. This is particularly true for eclipsing binaries (EBs), which form one of the most populated types of variable objects. The Gaia mission, launched at
Audard, M.   +13 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Qualitative Alterations on Corneal Endothelial Cell Morphometry and Hexagonality After Cataract Surgery

open access: yesClinical Ophthalmology, 2021
Francesco Saverio Sorrentino Department of Surgical Sciences, Unit of Ophthalmology, Ospedale Maggiore, Bologna, ItalyCorrespondence: Francesco Saverio Sorrentino Email dr.fsorrentino@gmail.comAim: To deeply analyze quantitative and qualitative changes ...
Sorrentino FS
doaj  

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status

open access: yesJournal of Translational Medicine, 2011
Background The detection of insulin autoantibodies (IAA) aids in the prediction of autoimmune diabetes development. However, the long-standing, gold standard 125I-insulin radiobinding assay (RBA) has low reproducibility between laboratories, long sample ...
Lo Bernice   +14 more
doaj   +1 more source

Use of Eye-Tracking Technology to Investigate Cognitive Load Theory

open access: yes, 2018
Cognitive load theory (CLT) provides us guiding principles in the design of learning materials. CLT differentiates three different kinds of cognitive load -- intrinsic, extraneous and germane load.
Hutson, John   +3 more
core   +1 more source

Phosphodiesterase-4 inhibition reduces ECLS-induced vascular permeability and improves microcirculation in a rodent model of extracorporeal resuscitation [PDF]

open access: yesAmerican Journal of Physiology-Heart and Circulatory Physiology, 2019
Extracorporeal circulation can be accompanied by increased vascular permeability leading to pathological fluid balance and organ dysfunction. The second messenger cAMP is involved in capillary permeability and maintains endothelial integrity. The aim of the present study was to evaluate the effect of phosphodiesterase-4 (PDE4) inhibition with rolipram
Jakob Wollborn   +5 more
openaire   +3 more sources

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