Results 61 to 70 of about 212,448 (296)

Phosphodiesterase-4 inhibition reduces ECLS-induced vascular permeability and improves microcirculation in a rodent model of extracorporeal resuscitation [PDF]

American Journal of Physiology-Heart and Circulatory Physiology, 2019
Extracorporeal circulation can be accompanied by increased vascular permeability leading to pathological fluid balance and organ dysfunction. The second messenger cAMP is involved in capillary permeability and maintains endothelial integrity. The aim of the present study was to evaluate the effect of phosphodiesterase-4 (PDE4) inhibition with rolipram
Jakob Wollborn, Svenja Siemering, Christoph Steiger, Hartmut Buerkle, Ulrich Goebel, Martin A. Schick   +5 more
openaire   +3 more sources

Modeling Theories and Theorizing Models: an Attempted Replication of Miller-Cotto & Byrnes’ (2019) Comparison of Working Memory Models Using ECLS-K Data

Educational Psychology Review, 2021
Working memory is an essential mechanism in the cognitive learning process. However, its definitions and mechanisms remain a topic of debate. Miller-Cotto and Byrnes (Journal of Educational Psychology, 112(5), 1074–1084, 2020) reported a comparison of three models of working memory to determine which best accounted for data obtained from a national US ...
David F. Feldon, Kaylee Litson
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Qualitative Alterations on Corneal Endothelial Cell Morphometry and Hexagonality After Cataract Surgery

Clinical Ophthalmology, 2021
Francesco Saverio Sorrentino Department of Surgical Sciences, Unit of Ophthalmology, Ospedale Maggiore, Bologna, ItalyCorrespondence: Francesco Saverio Sorrentino Email dr.fsorrentino@gmail.comAim: To deeply analyze quantitative and qualitative changes ...
Sorrentino FS
doaj  

Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status

Journal of Translational Medicine, 2011
Background The detection of insulin autoantibodies (IAA) aids in the prediction of autoimmune diabetes development. However, the long-standing, gold standard 125I-insulin radiobinding assay (RBA) has low reproducibility between laboratories, long sample ...
Lo Bernice, Swafford Austin DE, Shafer-Weaver Kimberly A, Jerome Lawrence F, Rakhlin Luba, Mathern Douglas R, Callahan Conor A, Jiang Ping, Davison Lucy J, Stevens Helen E, Lucas Carrie L, White Jill, von Borstel Reid, Todd John A, Lenardo Michael J   +14 more
doaj   +1 more source

Deep Learning-Based Security Verification for a Random Number Generator Using White Chaos

Entropy, 2020
In this paper, a deep learning (DL)-based predictive analysis is proposed to analyze the security of a non-deterministic random number generator (NRNG) using white chaos.
Cai Li, Jianguo Zhang, Luxiao Sang, Lishuang Gong, Longsheng Wang, Anbang Wang, Yuncai Wang   +6 more
doaj   +1 more source

MODELING TRANSITING CIRCUMSTELLAR DISKS: CHARACTERIZING THE NEWLY DISCOVERED ECLIPSING DISK SYSTEM OGLE LMC-ECL-11893 [PDF]

The Astrophysical Journal, 2014
We investigate the nature of the unusual eclipsing star OGLE LMC-ECL-11893 (OGLE J05172127-6900558) in the Large Magellanic Cloud recently reported by Dong et al. 2014. The eclipse period for this star is 468 days, and the eclipses exhibit a minimum of ~1.4 mag, preceded by a plateau of ~0.8 mag.
Erin L. Scott, Eric E. Mamajek, Mark J. Pecaut, Alice C. Quillen, Fred Moolekamp, Cameron P. M. Bell   +5 more
openaire   +2 more sources

Model oczekiwanych strat kredytowych w sprawozdawczości finansowej

, 2021
Międzynarodowy Standard Sprawozdawczości Finansowej 9 „Instrumenty finansowe” wprowadził nowy model określania odpisów aktualizujących wartość aktywów oraz ujmowania rezerw na gwarancje finansowe i zobowiązania do udzielenia pożyczek, znany jako model ...
Frendzel, Maciej
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source