Results 131 to 140 of about 181,436 (309)

GOLD Observations of Thermospheric Neutral Temperature Variability During the 14 October 2023 Annular Solar Eclipse

open access: yesGeophysical Research Letters
The 14 October 2023 annular solar eclipse was visible from the US Pacific coast to Brazil's east coast. NASA's Global‐scale Observations of Limb and Disk (GOLD) mission observed the first synoptic thermospheric temperature changes from a geo‐stationary ...
Saurav Aryal   +6 more
doaj   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

MrEclipse.com: The Ultimate Resource for Eclipse Photography

open access: yes
MrEclipse.com provides a guide to solar and lunar eclipses, eclipse photo galleries, and a travel section on future eclipse expeditions. There are links to NASA webpages on upcoming eclipses, and reports on past eclipses.
Fred Espenak
core  

Business process Eclipse Editor (BEE)

open access: yes, 2008
An important aspect of business process modelling is let non-professional users understand business processes, so that they can be involved not only in their understanding but even in their management.
A. Donatelli   +5 more
core  

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

open access: yesAdvanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida   +4 more
wiley   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru   +2 more
wiley   +1 more source

Solar-eclipse-induced perturbations at mid-latitude during the 21 August 2017 event

open access: yes, 2019
A study of the response of some ionospheric parameters and their relationship in describing the behaviour of ionospheric mechanisms during the solar eclipse of 21 August 2017 is presented.
Ikubanni, SO (15713834)   +6 more
core  

Studying the Radio Eclipse of Spider Pulsar J1816+4510 with the FAST

open access: yesThe Astrophysical Journal
We report on the radio eclipse properties of spider pulsar J1816+4510 using the Five-hundred-meter Aperture Spherical radio Telescope (FAST). The high-sensitivity FAST observations will allow us to probe much deeper into the eclipse region of this pulsar
Lunhua Shang   +10 more
doaj   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

open access: yesAdvanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng   +12 more
wiley   +1 more source

The Ivory Tower, Trump, and the Eclipse of Dignity [PDF]

open access: yes, 2017
The Eclipse of Dignity Part 2: If a Trump win came partly as a reaction to ‘the PC brigade’, it has to be said they presented an easy ...
Eden, Michael
core  

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