Results 151 to 160 of about 198,418 (346)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

HF Radar Observations and Modeling of the Impact of the 8 April 2024 Total Solar Eclipse on the Ionosphere‐Thermosphere System

Geophysical Research Letters
The path of totality of the 8 April 2024 solar eclipse traversed the fields‐of‐view of four US SuperDARN radars. This rare scenario provided an excellent opportunity to monitor the large‐scale ionospheric response to the eclipse.
B. S. R. Kunduri, J. B. H. Baker, J. M. Ruohoniemi, E. G. Thomas, J. D. Huba, D. J. Emmons, D. R. Themens, K. T. Sterne, G. Farinas Perez, W. A. Bristow, S. G. Shepherd, J. M. Holmes, E. V. Dao, A. T. Chartier, G. W. Perry, K. Pandey   +15 more
doaj   +1 more source

MrEclipse.com: The Ultimate Resource for Eclipse Photography

MrEclipse.com provides a guide to solar and lunar eclipses, eclipse photo galleries, and a travel section on future eclipse expeditions. There are links to NASA webpages on upcoming eclipses, and reports on past eclipses.
Fred Espenak
core  

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

GOLD Observations of Thermospheric Neutral Temperature Variability During the 14 October 2023 Annular Solar Eclipse

Geophysical Research Letters
The 14 October 2023 annular solar eclipse was visible from the US Pacific coast to Brazil's east coast. NASA's Global‐scale Observations of Limb and Disk (GOLD) mission observed the first synoptic thermospheric temperature changes from a geo‐stationary ...
Saurav Aryal, J. Scott Evans, Jerry D. Lumpe, Fazlul I. Laskar, Quan Gan, Wenbin Wang, Richard W. Eastes   +6 more
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Agent-Based Business Process Management with Eclipse

, 2011
This paper describes WOLF (WOrkflow LiFe cycle management environment), an open-source development environment that leverages the full power of Eclipse to provide users with an industrial-strength business process modelling tool that has already proven ...
D. Gotta, BERGENTI, Federico, G. Sacchi, E. Quarantotto, G. Caire   +4 more
core  

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Business process Eclipse Editor (BEE)

, 2008
An important aspect of business process modelling is let non-professional users understand business processes, so that they can be involved not only in their understanding but even in their management.
A. Donatelli, A. Cotugno, S. Mignogna, R. Longobardi, R. Gangemi, MARESCA, PAOLO   +5 more
core