Results 201 to 210 of about 45,653 (253)
Advanced Science, EarlyView.Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu +14 more
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Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer
Advanced Science, EarlyView.Warburg effect‐derived lactate drives HER2 lactylation and trastuzumab resistance. Mechanistically, AARS1‐mediated lactylation stabilizes HER2 by inhibiting USP11‐dependent degradation and concurrently promotes HER2‐EGFR interaction. Importantly, inhibiting HER2 lactylation resensitizes gastric cancer cells to trastuzumab.
Meng Qian +11 more
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Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics
Advanced Science, EarlyView.Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan +5 more
wiley +1 more source
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Review of Scientific Instruments, 1933
info:eu-repo/semantics ...
Bourgeois, Paul, Cox, Jacques
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info:eu-repo/semantics ...
Bourgeois, Paul, Cox, Jacques
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Eclipse Cycles and Eclipses at Stonehenge
Nature, 1967Was Stonehenge used to predict eclipses? Previous claims have assumed a high degree of sophistication on the part of the builders of Stonehenge, and that the number of Aubrey holes (56) is particularly significant. It may be that neither assumption is justified or necessary, and that if the builders of Stonehenge did predict eclipses, they did it in ...
R. COLTON, R. L. MARTIN
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Annular Eclipses — and Eclipse Photography
1998Annular eclipses are more frequent than total eclipses, simply because the average length of the Moon’s shadow is not quite long enough to touch the surface of the Earth, but from any particular locality even annulars are not common. Over England, the last was in 1858; the next will not be until 2093.
Michael Maunder, Patrick Moore
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Eclipsing the Eclipse?: A Neo-Darwinian Historiography Revisited
Journal of the History of Biology, 2021Julian Huxley's eclipse of Darwinism narrative has cast a long shadow over the historiography of evolutionary theory around the turn of the nineteenth century. It has done so by limiting who could be thought of as Darwinian. Peter Bowler used the eclipse to draw attention to previously understudied alternatives to Darwinism, but maintained the same ...
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2021
In 2001, there was a total solar eclipse on the Earth, and this gave us the opportunity to invent a “dish for the eclipse”. Here is the recipe, based on the idea that compounds are differently released by solutions, emulsions, gels … This idea is indeed an application of the ideas that are developed in the chapters on disperse system formalism (DSF ...
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In 2001, there was a total solar eclipse on the Earth, and this gave us the opportunity to invent a “dish for the eclipse”. Here is the recipe, based on the idea that compounds are differently released by solutions, emulsions, gels … This idea is indeed an application of the ideas that are developed in the chapters on disperse system formalism (DSF ...
openaire +2 more sources
2021
This chapter focuses on Patricia Burke Brogan’s Eclipsed, which premiered in Galway and Edinburgh in 1992. Eclipsed highlights the injustice and cruelty inherent in the Magdalen institutions at a time when some laundries were still functioning. Interestingly, Burke Brogan may be considered a witness as well as a playwright; as a novice nun in the late ...
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This chapter focuses on Patricia Burke Brogan’s Eclipsed, which premiered in Galway and Edinburgh in 1992. Eclipsed highlights the injustice and cruelty inherent in the Magdalen institutions at a time when some laundries were still functioning. Interestingly, Burke Brogan may be considered a witness as well as a playwright; as a novice nun in the late ...
openaire +1 more source
Mechanisms for eclipsing in exotic eclipsing systems
Astrophysics, 2006The stars e Aur, KH 15D, and H 187 are utterly different in their fundamental characteristics. However, they share two important features: (1) prolonged eclipses are observed in all three and (2) there are no spectroscopic signs of a second component.
V. P. Grinin, L. V. Tambovtseva
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