Results 181 to 190 of about 198,418 (346)

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong   +13 more
wiley   +1 more source

Automated EQD<sub>2</sub> reporting for cervical cancer high-dose-rate brachytherapy using a standalone ESAPI-based application. [PDF]

open access: yesJ Contemp Brachytherapy
Pavičar B   +8 more
europepmc   +1 more source

An EMF Framework for Event-B

open access: yes, 2010
The Rodin platform for Event-B formal modelling is based on a bespoke model repository. While this approach has some advantages it also means that the platform does not benefit from the host of emerging technologies and supporting packages that are ...
Snook, Colin   +2 more
core  

Real‐Time Ferroelectric Domain Wall Dynamics During Electric Poling and Depoling

open access: yesAdvanced Science, EarlyView.
Real‐time visualization of domain wall dynamics during alternating‐current poling, direct‐current poling, and electrical depoling in relaxor‐PT ferroelectric single crystals reveals distinct field‐dependent pathways and strong path dependence. Instant polarized light microscopy uncovers reversible domain wall nucleation, motion, and reconfiguration ...
Ziqi Wang   +12 more
wiley   +1 more source

Respiratory oscillometry in patients with chronic obstructive pulmonary disease with airway mucus plugs: insights from the ECLIPSE study. [PDF]

open access: yesAm J Respir Crit Care Med
Olanipekun T   +9 more
europepmc   +1 more source

vLab: an Eclipse-based Virtual Laboratory

open access: yes, 2007
In modern education, and especially in the Computer Engineering field, integrating conceptual understanding with technical skills assumes a strategic importance.
RICCIONI, ANNA, DENTI, ENRICO
core  

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

open access: yesAdvanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa   +5 more
wiley   +1 more source

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