Results 181 to 190 of about 181,436 (309)

Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective

Advanced Science, EarlyView.
This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin, Yingqiao Liu, Haitao Lin, Kang Feng, Xiqiang Liu   +4 more
wiley   +1 more source

Implementing digital interventions for co-occurring mental health and alcohol and other drug use problems in health and community settings: a study protocol for the eCliPSE cluster randomised controlled trial. [PDF]

BMC Public Health
Heinsch M, Wells H, Tickner C, Sampson DL, Rich J, Carlson J, Teesson M, Mihalopoulos C, Sunderland M, Christensen H, Haber P, Morley K, Baillie A, Wyllie J, Shaw T, Chatterton ML, Corliss C, Gulhati G, Simmonette D, Hunt S, Thornton L, Kay F.   +21 more
europepmc   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Evaluation of Epithelial Integrity in Human Precision-Cut Kidney Slices. [PDF]

APMIS
Pedersen GA, Green BB, Merrild C, Elsborg SH, Madsen MG, Keller AK, Mutsaers HAM, Nørregaard R, Nejsum LN.   +8 more
europepmc   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

Delay Correction Method Based on VLF Timing Signal Phase Variation Model. [PDF]

Sensors (Basel)
Ma X, Yan W, Hu Z, Yuan J, Hua Y, Li S.
europepmc   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Efforts to Secure Nicotine and Cannabis Product Placements in Popular Media by Ploom, Pax, and Juul: An Analysis of Tobacco Industry Documents. [PDF]

Nicotine Tob Res
Wakefield T, Bialous S, Ling P, Apollonio DE.   +3 more
europepmc   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

Batch Export: An automated framework for curated data extraction via the Eclipse treatment planning system. [PDF]

J Appl Clin Med Phys
Truong R, Moore LC, Bojechko C, Meyers SM, Kisling K, Ray X.   +5 more
europepmc   +1 more source