Results 181 to 190 of about 438,913 (286)

Prognostic score for predicting respiratory admissions among patients with chronic obstructive pulmonary disease in primary care: development and validation in population cohorts (Birmingham Lung Improvement Studies (BLISS)).

BMJ
Jordan RE, Keene SJ, Franssen FME, Fitzmaurice D, Adderley NJ, Dickens AP, Martin JT, Sitch AJ, Enocson A, Jowett S, Riley RD, Miller MR, Cooper BG, Turner A, Jolly K, Ayres JG, Stockley R, Greenfield S, Siebert S, Daley A, Cheng KK, de Vries F, Wouters EFM, Adab P.   +23 more
europepmc   +1 more source

A safe seal: controlled flow arrest with dual balloon protection for embolisation of a large spontaneous splenic arteriovenous fistula-a case report. [PDF]

CVIR Endovasc
Vijayasekar P, Jagannathan T, Kulanthaivelu K, Sekar S, Joseph A.   +4 more
europepmc   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Breaking barriers in crosslinking mass spectrometry with enhanced throughput and sensitivity using Orbitrap Astral. [PDF]

Nat Commun
Müller F, Birklbauer MJ, Bubis J, Stejskal K, Dorfer V, Mechtler K.   +5 more
europepmc   +1 more source

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Desargues cloud TPS: a cloud-based automatic radiation treatment planning system for IMRT. [PDF]

Biomed Eng Online
Guo J, Qin S, Guo C, Zhu M, Zhou Y, Wang H, Xu X, Zhan W, Chen L, Ni J, Tang Y, Chen J, Shen Y, Chen H, Men K, Liu H, Pan Y, Ye J, Huan J, Zhou J.   +19 more
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Evaluation of deliverable dose-mimicking automated volumetric arc radiation therapy planning for stage III non-small cell lung cancer patients: comparison with a commercial DVH-predicted automated planning system. [PDF]

J Radiat Res
Nakajima T, Kadoya N, Tozuka R, Kondo M, Tanaka S, Arai K, Katsuta Y, Hoshino T, Yamamoto T, Jingu K.   +9 more
europepmc   +1 more source

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

ACOSA: A Script-Based Algorithm for Multi-Disease Target Crop and Optimization in Radiotherapy. [PDF]

Technol Cancer Res Treat
Guo H, Xiao Z, Zhou H, Wang Y, Wang M, Lin X, Liu J, Li X, Xue X.   +8 more
europepmc   +1 more source