Results 31 to 40 of about 45,653 (253)

Proper pandemic preparedness requires an integrated cross-regional effort, the case of the ECLIPSE consortium in America: a narrative review

open access: yesJournal of Health, Population and Nutrition
Background Emerging and re-emerging infectious diseases pose significant threats to global public health, economic stability, and security. This paper focuses on three critical examples: Highly Pathogenic Avian Influenza (HPAI), Dengue Fever (DF), and ...
Alejandro Bernardin   +5 more
doaj   +1 more source

Three dimensional modeling and controlling of bridge-detection vehicle(Eclipse环境下桥梁检测车三维模型的构建与控制)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2013
针对桥梁检测车操作人员无法直接观察桥检车机械臂的动作状态的问题,提出构建桥检车的三维模型,能够实时动态地跟踪显示出桥检车机械臂的动作状态.以Eclipse作为软件开发平台,基于OpenGL ES实现桥检车的三维模型构建和控制给出直接三维建模法与插件三维建模法.实验结果表明,2种方法均可实现桥检车三维模型的构建与控制,对于规则三维模型的构建与控制,直接三维建模法要优于插件三维建模法.
WANGXiu-min(王秀敏)   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

An Eclipse Environment for Z [PDF]

open access: yes, 2006
This thesis reports on the design, implementation and evaluation of a new interactive Z environment that is integrated into the Eclipse environment.
Xu, Chengdong
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Biophysical modeling for accurate T cell specificity prediction of viral and tumor antigens

open access: yesNature Communications
We develop and apply a dual experimental and computational framework to predict antigen specificity of TCR sequences in serial clinical samples. Our model integrates TCR primary sequences with previously reported and in silico-derived TCR-pMHC structural
Zahra S. Ghoreyshi   +13 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Technical Note: An Eclipse Scripting Application Programming Interface-based Tool for Automated Structure Duplication, Cropping, and Ring Generation in Eclipse Treatment Planning System

open access: yesJournal of Medical Physics
Introduction: Structure duplication and margin-based cropping are routine but time-consuming steps in inverse treatment planning using the Eclipse treatment planning system (TPS).
Deepak Mahor, Vinay Saini
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

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