Results 201 to 210 of about 5,777 (259)

A New Era in Treponema pallidum Cultivation: Current Advances and Future Directions. [PDF]

Sex Transm Dis
Hawley KL, Grillová L, Giacani L, Norris SJ.   +3 more
europepmc   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

Nanobodies unlock new mechanisms to target G protein-coupled receptors. [PDF]

Mol Pharmacol
Skiba MA.
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Association of Hemodynamic Parameters with Clinical Outcomes in Cardiogenic Shock: Insights from Full-Flow Micro-Axial Flow Pump Data in a Retrospective Single-Center Study. [PDF]

J Clin Med
Riebandt J, Moayedifar R, Ruoff L, Al Asadi H, Söllner S, Saleh R, Seibert O, Karner B, Schaefer AK, Zimpfer D, Schlöglhofer T.   +10 more
europepmc   +1 more source

Short-Term Percutaneous Mechanical Circulatory Support in Acute Coronary Syndrome with Cardiogenic Shock: Which Device to Choose? [PDF]

J Cardiovasc Dev Dis
Tetaj N, Nusca A, Piccirillo F, Halasz G, Gabrielli D, Ussia GP, Grigioni F.   +6 more
europepmc   +1 more source

Outcomes and prediction of mortality in patients requiring prolonged veno-arterial extracorporeal membrane oxygenation support in the PRECISE-ECLS observational study. [PDF]

Crit Care
Bunge JJH, Pladet LCA, Luijken K, Van Steenwijk MPJ, Van Esch A, Elzo Kraemer CV, Maas JJ, Dos Reis Miranda D, Dubois EA, Caliskan K, Montenij LJ, Otterspoor LC, Scholten E, Van Koppenhagen L, Cremer OL, Gommers D, Donker DW, Meuwese CL.   +17 more
europepmc   +1 more source

Extracorporeal Membrane Oxygenation in Acute Cardiovascular Care. [PDF]

Circ Rep
Tateishi K, Saito Y, Kato K, Kitahara H, Kobayashi Y.   +4 more
europepmc   +1 more source

Early Reading and Math Developmental Trajectories: Examining Influences of Specific Learning Disabilities and Socioeconomic Status. [PDF]

J Learn Disabil
Marks RA, Woods AD, Mesite L, Fox AB, Christodoulou JA.   +4 more
europepmc   +1 more source