Results 41 to 50 of about 51,857 (251)

ECMO or no ECMO: Do no harm

Anales de Pediatría, 2002
Extracorporeal membrane oxygenation (ECMO) has been used in the management of neonates with life-threatening cardiorespiratory diseases since 19821 . Several studies have demonstrated that ECMO promotes normal survival in neonates with respiratory failure2-4 .
openaire   +2 more sources

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Assessing Kidney Transplantation Using ECMO-Supported Donors Within a KDPI-Based Allocation System

Transplantation Direct, 2023
Background. Organ donors supported by extracorporeal membrane oxygenation (ECMO) have historically been considered high-risk and are judiciously utilized.
Peter J. Altshuler, MD, Devon J. Pace, MD, William A. Preston, MD, Sage A. Vincent, MD, Ashesh P. Shah, MD, Jaime M. Glorioso, MD, Warren R. Maley, MD, Adam M. Frank, MD, Carlo B. Ramirez, MD, Sharon West, MS, Richard Hasz, Jr, MFS, CPTC, Adam S. Bodzin, MD   +11 more
doaj   +1 more source

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source

Ecmo in a diabetic patient with cerebellar infarction and ARDS-A case report [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background: Extra corporeal membrane oxygenation (ECMO) has been considered as a crucial modality for the management of acute respiratory distress syndrome (ARDS).
Reza Nikandish, Farid Zand, Golnar Sabetian, Mansoor Masjedi, Mandana Mackie, Elham Asadpour   +5 more
doaj   +2 more sources

Canulación yugulo-subclavia de ECMO-VA en shock cardiogénico por tromboembolia pulmonar y síndrome de hipercoagulabilidad

Revista Colombiana de Cardiología
El uso de soporte vital extracorpóreo es una opción en pacientes con shock cardiogénico secundario a insuficiencia ventricular derecha y tromboembolia pulmonar.
Leonardo A. Salazar-Rojas, Juan Porras, Claudia C. Colmenares-Mejía, Valentina Pinzón   +3 more
doaj   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

The Predictive Power of Barotrauma from the Macklin Effect in the ARDS Population: A Comparison of COVID-19 and Non-COVID-19 ARDS—Could the Macklin Effect Serve as a Helpful Tool for Evaluating Transfer to ARDS Reference Centers?

Diagnostics
Background: The Macklin effect recently demonstrated a high positive predictive value for barotrauma in the COVID-19 ARDS population. However, there was less evidence available regarding the ARDS population without SARS-CoV-2 infection. We aim to analyze
Alberto Marabotti, Filippo Pelagatti, Gianluca Frezzetti, Marco Albanesi, Antonio Galluzzo, Alessandra Valletta, Laura Arianna Sorrentino, Andrea Cardoni, Giovanni Cianchi, Marco Ciapetti, Chiara Lazzeri, Adriano Peris, Manuela Bonizzoli   +12 more
doaj   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

EXTRACORPOREAL MEMBRANE OXYGENATION AS A METHOD OF TEMPORARY MECHANICAL CIRCULATORY SUPPORT IN PATIENTS WITH END-STAGE HEART FAILURE

Клінічна та профілактична медицина
Introduction. Mechanical circulatory support systems are used in three categories of patients. The first group includes patients who cannot be weaned off the circulatory support machine after open-heart surgery (2–8% of patients).
Volodymyr G. Tansky, Olga O. Tanska, Taras V. Okun, Serhiy V. Prudkoy   +3 more
doaj   +1 more source