Results 101 to 110 of about 1,121,732 (311)

Synthetic ShK-like Peptide from the Jellyfish Nemopilema nomurai Has Human Voltage-Gated Potassium-Channel-Blocking Activity

Marine Drugs
We identified a new human voltage-gated potassium channel blocker, NnK-1, in the jellyfish Nemopilema nomurai based on its genomic information. The gene sequence encoding NnK-1 contains 5408 base pairs, with five introns and six exons.
Ye-Ji Kim, Yejin Jo, Seung Eun Lee, Jungeun Kim, Jae-Pil Choi, Nayoung Lee, Hyokyoung Won, Dong Ho Woo, Seungshic Yum   +8 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Temporal Evolution, Source Apportionment, and Health Risks of Atmospheric Halocarbons: A Case Study in the Central Yangtze River Delta Region

Toxics
Recently, the environmental impact of halocarbons has become increasingly concerning, particularly due to the growing influence of non-regulated halocarbons on stratospheric ozone depletion and their adverse health effects in the troposphere.
Yuchun Jiang, Anqi Zhang, Qiaoli Zou, Hanfei Zuo, Jinmei Ding, Lu Zhang, Lingling Jin, Da Xu, Yuwen Niu, Bingye Xu, Xiaoqian Li   +10 more
doaj   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Comparative Study on the Characteristics of Bacterial and Microeukaryotic Communities in Aquaponics and Recirculating Aquaculture Systems [PDF]

Progress in Fishery Sciences
The aquaponics system, an integrated ecological agriculture model, effectively combines aquaculture and the cultivation of aquatic plants. This system not only utilizes the nutrients in aquaculture water to promote plant growth but also purifies water ...
FAN Dingyue, XU Huimin, MENG Shunlong, FAN Limin, SONG Chao, QIU Liping, LI Dandan, FANG Longxiang, LIU Zhuping, BING Xuwen   +9 more
doaj   +1 more source

Modelling the behaviour of nutrients in the coastal waters of Scotland [PDF]

, 2002
The overall goal of this project was to provide Scotland with a strategic ecosystem simulation tool for identifying maritime areas which could be at risk of eutrophication.
Edwards, A.C., Heath, M.R., Patsch, J., Scottish Executive Central Research Unit (Funder), Turrell, W.R.   +4 more
core  

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Freshwater water quality criteria for phthalate esters and recommendations for the revision of the water quality standards

Ecotoxicology and Environmental Safety
With increasing urbanization and rapid industrialization, more and more environmental problems have arisen. Phthalates (PAEs) are the foremost and most widespread plasticizers and are readily emitted from these manufactured products into the environment.
Yajun Hong, Sa Xiao, Saraschandra Naraginti, Wei Liao, Chenglian Feng, Dayong Xu, Changsheng Guo, Xiaowei Jin, Fazhi Xie   +8 more
doaj   +1 more source

Four major task domains of science for sustainability [PDF]

We propose a research agenda integrating environment-related science, technology, and innovation (STI) using a problem-solving approach to sustainable development.
Jappe-Heinze, Arlette
core  

Global Nitrogen Deposition Promotes Carbon Sink Formation in Terrestrial Ecosystems

Advanced Science, EarlyView.
Nitrogen deposition alleviates ecosystem N limitation and enhances carbon sinks. Using 829 observations, we show 36% of deposited N is retained globally (39.15 Tg N yr−1), with distinct NHx and NOy contributions. This retention drives a terrestrial C sink of 0.88 Pg C yr−1 (25.48%), highlighting the importance of pool‐specific C:N stoichiometry ...
Lei Li, Mingyu Xie, Nan Jia, Li‐Dong Mo, Qiang Yu, Fanjiang Zeng, Xiangyi Li   +6 more
wiley   +1 more source