Results 81 to 90 of about 4,763,301 (244)

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

open access: yesAdvanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao   +20 more
wiley   +1 more source

Spatiotemporal Pattern and Obstacle Factors of Land Eco-Security Early Warning in Henan Province

open access: yesShuitu baochi yanjiu, 2020
The rapid progress of the urbanization and industrialization of the Central Plains Economic Zone has led to increasing pressure on the regional ecological environment, and it is necessary to carry out early warning and assessment of the security of land ...
WEI Yuchan, ZHANG Liqin
doaj  

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

open access: yesAdvanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen   +6 more
wiley   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

open access: yesAdvanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou   +4 more
wiley   +1 more source

Assessment of Multiple Ecosystem Services and Ecological Security Pattern in Shanxi Province, China. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Wang J, Li Y, Wang S, Li Q, Li L, Liu X.
europepmc   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang   +9 more
wiley   +1 more source

Texas National Security Review: Shaping Security Vol. 8, Issue 4, 2025

open access: yes
TABLE OF CONTENTS: THE FOUNDATION pg.2 What Do We Really Know? By Francis J. Gavin THE SCHOLAR Pg.8 Hard Then, Harder Now: CoCom’s Lessons and the Challenge of Crafting Effective Export Controls Against China by Jennifer Lind and Michael Mastanduno ...
Texas National Security Review
core   +1 more source

Changing Homeland Security: Ten Essential Homeland Security Books [PDF]

open access: yes, 2007
This article appeared in Homeland Security Affairs (February 2007) v.3 no.1This article presents what I consider to be ten essential homeland security books. The list is personal and provisional. The discipline is too new to have a canon.
Bellavita, Christopher
core   +2 more sources

Construction of landscape ecological network based on MCR risk assessment Model: A case study of Liaoning Province, China

open access: yesEcological Indicators
Numerous disorderly expansions of impervious surfaces have resulted from the ongoing urbanization process, eroding the ecological security pattern and exacerbating ecological risks, subsequently leading to a progressive deterioration in its integrity ...
Shuhan Zhang   +4 more
doaj   +1 more source

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