Results 1 to 10 of about 19,343 (112)

MCR Expression Conferring Varied Fitness Costs on Host Bacteria and Affecting Bacteria Virulence

Antibiotics, 2021
Since the first report of the plasmid-mediated, colistin-resistant gene, mcr-1, nine mcr genes and their subvariants have been identified. The spreading scope of mcr-1~10 varies greatly, suggesting that mcr-1~10 may have different evolutionary advantages.
Wan Li, Zhihai Liu, Wenjuan Yin, Lu Yang, Lu Qiao, Shikai Song, Zhuoren Ling, Ruicheng Zheng, Congming Wu, Yang Wang, Jianzhong Shen   +10 more
doaj   +3 more sources

Host-dependent effects of mcr-1 and mcr-8 on fitness, virulence, and transmission in Escherichia coli and Klebsiella pneumoniae [PDF]

Frontiers in Microbiology
IntroductionAs one of the most common groups of clinical pathogens, Enterobacterales pose a serious threat to global public health due to their multidrug-resistance.
Mengyu Zhou, Mengyu Zhou, Yining Ye, Nuoyou Cheng, Huangdu Hu, Xinhong Han, Qing Yu, Qing Yu, Yan Jiang, Yan Jiang, Yunsong Yu, Yunsong Yu, Dongdong Zhao, Dongdong Zhao, Jingjing Quan, Jingjing Quan   +15 more
doaj   +2 more sources

Macrophage-mediated antibiotic evasion and competitive dominance of mcr-3-carrying Escherichia coli. [PDF]

PLoS Pathogens
Mobile colistin resistance (mcr) genes compromise the efficacy of last-resort polymyxin antibiotics. Notably, the global prevalence of mcr-3 has continued to increase despite reductions in colistin use, suggesting that selective forces beyond direct ...
Shuyu Tan, Wenjuan Yin, Jian Sun, Wenguang Xiong, Yina An, Lu Qiao, Pu Zhang, Siqi Sun, Qianru Li, Leiming Fu, Yifan Liu, Yaqian Xue, Shuyi Huang, Yixi Liu, Yang Wang, Yanjun Dong   +15 more
doaj   +2 more sources

Clinical and neuroimaging correlates of motoric cognitive risk syndrome in cerebral small vessel disease: a cross-sectional study [PDF]

Frontiers in Aging Neuroscience
IntroductionCerebral small vessel disease (CSVD) and motoric cognitive risk syndrome (MCR) are both associated with adverse outcomes in older adults. Factors associated with MCR in CSVD remain poorly understood.
Huixin Zhang, Tong Guo, Ran Zhang, Hongyi Yan, Shuo Yang, Ying Gao, Tingting Wang, Weiqi Chen, Yuesong Pan, Yilong Wang, Yilong Wang, Weixin Cai, Ling Guan, Ling Guan, Ling Guan   +14 more
doaj   +2 more sources

Identification of the immunoprotective activity of Mori Cortex Radicis ethanol extract against aquaculture pathogens (Aeromonas veronii, Pseudomonas aeruginosa) [PDF]

Frontiers in Immunology
ObjectiveMori Cortex Radicis (MCR) is an important Chinese herbal medicine with antitussive, anti-inflammatory, and analgesic effects. It is abundant in resources and low in cost, but its application in the control of fish pathogens has been ...
Xing Zhang, Ling Zhu, Ling Zhu, Yixin Yu, Kai Wang, Kai Wang, Qinkai Hu, Xuan Huang, Guangbao Zhu, Jingjing Ma, Shanshan Li, Xiang Liu, Xiang Liu   +12 more
doaj   +2 more sources

Comprehensive and Non-Destructive Sweet Corn Shelf-Life Prediction Using Near-Infrared (NIR) Spectroscopy Coupled with Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) Spectral Resolution [PDF]

Molecules
Accurate shelf-life prediction of perishable products remains challenging because quality deterioration involves multiple physicochemical changes that are not adequately captured by conventional univariate approaches.
Sujitra Funsueb, Chanat Thanavanich, Chevaporn Chudoung, Phanaphon Jomnong, Parichat Theanjumpol, Sila Kittiwachana   +5 more
doaj   +2 more sources

Mechanochemically primed regenerative extracellular vesicles as a nanotherapeutic strategy for peripheral neuropathy [PDF]

Journal of Nanobiotechnology
Background Peripheral neuropathy is a chronic neurological disorder characterized by inflammation, nerve damage, and impaired function. It arises owing to various factors, including traumatic nerve injury, neuropathic pain due to cancer, and diabetic ...
Yeonjoo Kwak, Hye Min Jeun, Han Cheol Yeo, Sang-Hyeon Nam, Min-Ju Lee, Sujin Yu, Hyung Seok Choi, Ye Ji Han, Kwonwoo Song, Mi-Sook Chang, Ssang-Goo Cho   +10 more
doaj   +2 more sources

Association of physical activity with motoric cognitive risk syndrome among the middle-aged and older adults in China [PDF]

Scientific Reports
Motoric Cognitive Risk Syndrome (MCR) represents a pre-dementia syndrome amenable to intervention, bearing substantial public health significance in China amidst its rapidly aging population.
Weiyou Wang, Xiaowei Wei, Minxue Wu, Yandi Fu, Sitian Wu   +4 more
doaj   +2 more sources

Construction of Ecological Security Network Based on Minimum Cumulative Resistance Model at Ningbo City

Shuitu baochi tongbao, 2022
[Objective] An ecological safety network at Ningbo City, Zhejiang Province was constructed by identifying important ecological sources and potential ecological corridors in order to provide a reference for rationally guiding urban development and ...
Yu Menglin, Liu Pinghui, Zhu Chuanmin
doaj   +1 more source

The Mediating Role of Social Participation in Motoric Cognitive Risk and its Relation to Depression and Loneliness in Older Adults [PDF]

Annals of Geriatric Medicine and Research, 2023
Background Motoric cognitive risk syndrome (MCR) reduces the quality of life, independence, and social interaction in older adults. Social participation is a potentially modifiable factor that benefits cognitive and mental health. This study explored the
Ji Hyeun Park, Sangmi Park, Jae Hyu Jung, Suyeong Bae, Sohyeon Yun, Anastassiya Khan, Ickpyo Hong, Ji-Hyuk Park   +7 more
doaj   +1 more source