Results 91 to 100 of about 6,816 (172)

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

open access: yesObesity, Volume 34, Issue 7, Page 1420-1432, July 2026.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín   +4 more
wiley   +1 more source

Integrating Megabarcoding and Metabarcoding to Unlock Diversity and Distribution Data Shortfalls in Dark Taxa

open access: yesMolecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Persistent biodiversity data shortfalls undermine our capacity to detect species, map their distributions and characterize their spatial genetic structure, limiting robust biogeographic analyses and the development of effective conservation strategies.
I. Santos‐Perdomo   +12 more
wiley   +1 more source

Longitudinal Cognitive Evolution in Alcohol Use Disorder Patients: Role of Inflammation, Time of Abstinence and Apolipoprotein Profile

open access: yesAddiction Biology, Volume 31, Issue 7, July 2026.
Thirty‐three AUD patients enrolled in an Alcohol Detoxification Program at Hospital Universitario 12 de Octubre (Madrid, Spain) and 34 healthy controls were followed for 12 months. AUD patients exhibited impaired general cognitive functioning, elevated plasma LPS and altered apolipoproteins (APOAI, APOAE, APOAJ, APOAM), which progressively normalized ...
Berta Escudero   +3 more
wiley   +1 more source

El Costo total mínimo como criterio de eficiencia económica en el servicio de salud

open access: yesCiencias Holguín, 2012
El artículo presenta un nuevo punto de vista para analizar la eficiencia económica del servicio de salud desde el método de la optimización restringida.
Ramberto Rogelio Torres-Correa   +1 more
doaj  

Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias   +7 more
wiley   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

Integrated miRNA–mRNA Analysis Reveals Obesity‐Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5992-6008, July 2026.
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández   +19 more
wiley   +1 more source

Symbolic dimensions of health economics: connections with nursing work in hospitals. [PDF]

open access: yesRev Bras Enferm
Carneiro ADPR   +5 more
europepmc   +1 more source

[Economic evaluation in the health sector: The link between economic and health variables]. [PDF]

open access: yesRev Med Inst Mex Seguro Soc
Inzunza-Cervantes G   +2 more
europepmc   +1 more source

Patentes, suministro de medicamentos y protección de la salud publica [PDF]

open access: yesRevista Argentina de Salud Pública, 2011
Carlos , Correa   +8 more
doaj  

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