Results 91 to 100 of about 6,816 (172)
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín +4 more
wiley +1 more source
ABSTRACT Persistent biodiversity data shortfalls undermine our capacity to detect species, map their distributions and characterize their spatial genetic structure, limiting robust biogeographic analyses and the development of effective conservation strategies.
I. Santos‐Perdomo +12 more
wiley +1 more source
Thirty‐three AUD patients enrolled in an Alcohol Detoxification Program at Hospital Universitario 12 de Octubre (Madrid, Spain) and 34 healthy controls were followed for 12 months. AUD patients exhibited impaired general cognitive functioning, elevated plasma LPS and altered apolipoproteins (APOAI, APOAE, APOAJ, APOAM), which progressively normalized ...
Berta Escudero +3 more
wiley +1 more source
El Costo total mínimo como criterio de eficiencia económica en el servicio de salud
El artículo presenta un nuevo punto de vista para analizar la eficiencia económica del servicio de salud desde el método de la optimización restringida.
Ramberto Rogelio Torres-Correa +1 more
doaj
Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias +7 more
wiley +1 more source
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández +19 more
wiley +1 more source
Symbolic dimensions of health economics: connections with nursing work in hospitals. [PDF]
Carneiro ADPR +5 more
europepmc +1 more source
[Economic evaluation in the health sector: The link between economic and health variables]. [PDF]
Inzunza-Cervantes G +2 more
europepmc +1 more source
Patentes, suministro de medicamentos y protección de la salud publica [PDF]
Carlos , Correa +8 more
doaj

