Results 11 to 20 of about 61,834,618 (214)
Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease. [PDF]
Mov Disord Clin PractAbstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Ojeda-Lepe E +15 more
europepmc +2 more sources
Refining OVCAR-3 xenograft models of peritoneal carcinomatosis in nu/nu mice: Comparative intraperitoneal implantation strategies and the role of basement membrane matrix. [PDF]
Animal Model Exp MedA refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
Perelló-Trias MT +5 more
europepmc +2 more sources
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
El futuro de la economía de la salud
Lecturas de Economía, 2010 Este artículo aborda la economía de la salud como una ciencia del comportamiento y como insumo para la política y la investigación en servicios de la salud.
Victor R Fuchs
doaj +1 more source
Análisis de las cesáreas en Uruguay por tipo de centro hospitalario
Gaceta Sanitaria, 2019 Resumen: Objetivo: Analizar comparativamente la incidencia de las cesáreas en los subsistemas de salud de Uruguay y en relación con los estándares de la Organización Mundial de la Salud (OMS) considerando las características médico-obstétricas de los ...
Rafael Aguirre +2 more
doaj +1 more source
Atención Primaria, 2015 Objetivo: Evaluar la eficiencia de la terapia combinada de metformina y dapagliflozina, un nuevo antidiabético oral con un mecanismo de acción independiente de la insulina, en el tratamiento de la diabetes mellitus tipo 2 (DM2) en comparación con ...
Eduardo José Abad Paniagua +6 more
doaj +1 more source
Revista de Ciencias Sociales, 2006 Se presentan dos paradigmas de (meta-)economía comparados: el andino-tradicional y el cristiano-medieval. La mística cristiana medieval y la correspondiente ‘Economía de la Salud’ son comparadas con la cosmovisión (o ‘Pacha-vivencia’) andina y la ...
Juan van Kessel
doaj +1 more source
“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez +29 more
wiley +1 more source
Diagnostic accuracy of three technologies for the diagnosis of multi-drug resistant tuberculosis
Biomédica: revista del Instituto Nacional de Salud, 2017 Introduction: Multi-drug resistant (MDR-TB) and extensively drug-resistant (XDR-TB) tuberculoses are a global public health problem. Their timely detection might reduce the burden of the disease and the economic impact on health systems worldwide ...
Nelson José Alvis-Zakzuk +5 more
doaj +1 more source