Results 11 to 20 of about 6,816 (172)
Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
El futuro de la economía de la salud
Lecturas de Economía, 2010 Este artículo aborda la economía de la salud como una ciencia del comportamiento y como insumo para la política y la investigación en servicios de la salud.
Victor R Fuchs
doaj +1 more source
Análisis de las cesáreas en Uruguay por tipo de centro hospitalario
Gaceta Sanitaria, 2019 Resumen: Objetivo: Analizar comparativamente la incidencia de las cesáreas en los subsistemas de salud de Uruguay y en relación con los estándares de la Organización Mundial de la Salud (OMS) considerando las características médico-obstétricas de los ...
Rafael Aguirre +2 more
doaj +1 more source
Atención Primaria, 2015 Objetivo: Evaluar la eficiencia de la terapia combinada de metformina y dapagliflozina, un nuevo antidiabético oral con un mecanismo de acción independiente de la insulina, en el tratamiento de la diabetes mellitus tipo 2 (DM2) en comparación con ...
Eduardo José Abad Paniagua +6 more
doaj +1 more source
Diagnostic accuracy of three technologies for the diagnosis of multi-drug resistant tuberculosis
Biomédica: revista del Instituto Nacional de Salud, 2017 Introduction: Multi-drug resistant (MDR-TB) and extensively drug-resistant (XDR-TB) tuberculoses are a global public health problem. Their timely detection might reduce the burden of the disease and the economic impact on health systems worldwide ...
Nelson José Alvis-Zakzuk +5 more
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
The impact of obesity on health-related quality of life in Spain
Health and Quality of Life Outcomes, 2017 Background It is well documented that obesity is strongly associated with mortality and morbidity, but less is known about its impact on functional status and health-related quality of life (HRQOL).
Rafael Busutil +5 more
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Revista de Estudios Empresariales. Segunda ÉpocaObjetivo: La pandemia puso de manifiesto la necesidad de reforzar otro tipo de métodos docentes como son la docencia virtual, la gamificación o los formatos asíncronos.
David Cantarero Prieto +3 more
doaj +1 more source