Results 21 to 30 of about 6,816 (172)

Aspectos teóricos sobre la salud como un determinante del crecimiento económico

open access: yesLecturas de Economía, 2010
Las nuevas teorías del crecimiento económico y los desarrollos en la economía de la salud han planteado, de forma paralela, una relación recíproca entre la salud y el crecimiento.
Juan Miguel Gallego
doaj   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

open access: yesAdvanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García   +11 more
wiley   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Análisis de costo-efectividad de nilotinib, dasatinib e imatinib como terapia de primera línea en leucemia mieloide crónica en Colombia, 2012

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2014
Introducción. Los nuevos inhibidores de la tirosina cinasa para tratar la leucemia mieloide crónica basados en nilotinib, dasatinib e imatinib, mejoraron la calidad de vida de los pacientes y la tornaron en enfermedad crónica. Objetivo. Evaluar el costo-
Martín Romero   +3 more
doaj   +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory   +13 more
wiley   +1 more source

Stabilization Strategies for Carbon Based Perovskite Solar Cells Under Light, Heat, and Humidity

open access: yesEcoEnergy, EarlyView.
Carbon‐based MA1−x(AVA)xPbI3/CsPbBr3 QD heterostructures fabricated under ambient conditions exhibit < 5% loss under ISOS‐D‐3 and reversible photo‐induced degradation, revealing the dual role of QDs in defect passivation and dynamic interfacial stabilization.
Emilie Planes   +4 more
wiley   +1 more source

Diagnostic Performance of Comprehensive Point‐of‐Care Ultrasound for Pediatric Tuberculosis in Spain: A Prospective Observational Study

open access: yesJournal of Clinical Ultrasound, EarlyView.
In children with presumptive tuberculosis, comprehensive point‐of‐care (cPOCUS) identified key thoracic abnormalities with high specificity and excellent inter‐reader reliability. Although diagnostic sensitivity was modest and examinations often incomplete, cPOCUS shows promise as a complementary, radiation‐free imaging tool.
Isabelle Munyangaju   +17 more
wiley   +1 more source

Differential Progression of Neuroinflammation in Patients with Isolated Rapid‐Eye‐Movement Sleep Behavior Disorder

open access: yesMovement Disorders, EarlyView.
Abstract Background Neuroinflammation, measured using [11C](R)‐PK11195 positron emission tomography (PET), has been reported in isolated rapid‐eye‐movement sleep behavior disorder (iRBD), but its temporal progression is unknown. Objective The aim was to assess longitudinal progression of neuroinflammation in iRBD patients and its relationship with ...
Andreas Myhre Baun   +17 more
wiley   +1 more source

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