Results 51 to 60 of about 6,816 (172)

Cost-effectiveness of two antiviral therapies for chronic hepatitis B in Peru: entecavir and tenofovir

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2017
Objetives. To compare in terms of cost-effectiveness to entecavir (ETV) and tenofovir (TDF) in the treatment of hepatitis B virus (HBV) in public hospitals in Peru. Materials and methods. We structured a Markov model.
Rafael Bolaños-Díaz   +3 more
doaj   +1 more source

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

open access: yesAllergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez   +10 more
wiley   +1 more source

Factibilidad de implementar una intervención compleja para prevenir la intimidación entre pares en el ámbito escolar [PDF]

open access: yesRevista Argentina de Salud Pública, 2018
La intimidación entre estudiantes es un fenómeno que preocupa por su frecuencia y gravedad. OBJETIVOS: Diseñar y evaluar la factibilidad de una intervención compleja dirigida a reducir las situaciones de intimidación entre pares.
María Eugenia, Esandi   +7 more
doaj  

Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy

open access: yesAllergy, EarlyView.
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios   +24 more
wiley   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol   +6 more
wiley   +1 more source

Clinical Burden of Symptomatic HEV‐3 Infection in Southern Spain

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
María Casares‐Jimenez   +14 more
wiley   +1 more source

Cesni‐cel (ARI0002h) in ultra‐high‐risk multiple myeloma with plasma cell leukaemia or central nervous system involvement

open access: yesBritish Journal of Haematology, EarlyView.
ARI0002h induced response in 15/17 patients with plasma cell leukaemia (PCL)/central nervous system (CNS)‐multiple myeloma (MM) (87% achieved ≥ very good partial response [VGPR]) with a median progression‐free survival (PFS)/overall survival (OS) of 10.5 and 15.9 months respectively.
Carlos Jimenez‐Mira   +25 more
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

Prevalence, incidence and mortality of anaphylaxis in Colombia

open access: yesRevista Alergia México, 2018
Background: The lifetime prevalence of anaphylaxis from all triggers is estimated to range from 0.05 % to 2.6 %. Data on anaphylaxis in the Latin American region and Colombia are scant.
Pablo Andrés Miranda-Machado
doaj  

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

open access: yesBrain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios   +18 more
wiley   +1 more source

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