Results 31 to 40 of about 381,227 (307)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Unorthodox Thoughts on the Economic Crisis and the Dictum of Protagoras
Cadmus, 2018 The current economic crisis can be explained but we must remember that the crisis is the product of human behavior, both theoretical and practical, and not the product of some force of nature or mathematical law.
Gerald Gutenschwager
doaj
Studies in Business and Economics, 2018 In this study, we examine the impact of the 2008-2009 Global Crisis on poverty rates across the globe. Our results are mixed. We find that, after the crisis, there was a marginally significant increase in the number of the poorest group of people (living
Kaya Halil Dincer
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
The Global Economic Crisis And The Competiveness Of Polish Food Procuders
, 2012 The objective of this study is to show the influence of world economic crisis on economic situation of Polish food industry and competitiveness of Polish food producers. The study is an analysis based on statistical data.
Szczepaniak, Iwona
core +1 more source
Economic crisis, elite conflict and institutional change in empires
, 2023 The Ottoman and Habsburg Empires both faced the "general crisis" of the 17th century. Yet they responded to the crisis very differently. The Habsburgs centralized fiscal structures, which would facilitate economic development in the 19th century.
Demiryol, Tolga
core +1 more source
ECONOMIC CRISIS THEORY OR ECONOMIC THEORY CRISIS?
Globalization and Business, 2018 The global financial crisis has brought a new impulse to the discussion of the problem of economic crisis. Economists have divided into two groups - one group believes the main reason for the crisis is the failure of economic theory. The second group thinks that economists have not been charged in the formation of economic crisis.
openaire +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source