Results 41 to 50 of about 7,447,948 (300)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Unorthodox Thoughts on the Economic Crisis and the Dictum of Protagoras
Cadmus, 2018 The current economic crisis can be explained but we must remember that the crisis is the product of human behavior, both theoretical and practical, and not the product of some force of nature or mathematical law.
Gerald Gutenschwager
doaj
Studies in Business and Economics, 2018 In this study, we examine the impact of the 2008-2009 Global Crisis on poverty rates across the globe. Our results are mixed. We find that, after the crisis, there was a marginally significant increase in the number of the poorest group of people (living
Kaya Halil Dincer
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Economic crisis, elite conflict and institutional change in empires
, 2023 The Ottoman and Habsburg Empires both faced the "general crisis" of the 17th century. Yet they responded to the crisis very differently. The Habsburgs centralized fiscal structures, which would facilitate economic development in the 19th century.
Demiryol, Tolga
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Bulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law, 2021 The COVID-19 pandemic has a strong impact on each individual, but also on society as a whole, on all fields of human activity, including economic activity and performance. This challenge came less than 10 years after the end of
Ramona Ciobanu
doaj +1 more source
THE ECONOMIC CRISIS VERSUS THE CRISIS OF ECONOMICS AS A SCIENCE
Ekonomika, 2013 Abstract. The paper starts with arguments against forming causative links between crisis phenomena in the economy, both in its real and regulatory sphere, and the crisis of the economic science as such, in terms of its cognitive and predictive values.
openaire +3 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Oeconomia Copernicana, 2013 Croatia is becoming the 28th member of the European Union on July1st, 2013. Croatia has gone a long way from a socialist republic to an independentcountry recognized as one of the economic tigers of the Western Balkans in thefirst decade of the 21st century.Croatia has been hit by the global crisis, which turned out to be a huge externalshock for the ...
openaire +2 more sources