Results 31 to 40 of about 5,497,343 (307)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Do economic crises lead to health and nutrition behavior responses?: analysis using longitudinal data from Russia [PDF]
, 2013 Using longitudinal data on more than 2,000 Russian families spanning the period between 2007 and 2010, this paper estimates the impact of the 2009 global financial crisis on food expenditures, health care expenditures, and doctor visits in Russia.
Ajwad, Mohamed Ihsan +2 more
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Knowledge in Economics and Economic Reform: An Analysis of French Survey Data [PDF]
SSRN Electronic Journal, 2011 The coexistence of a predominantly poor opinion of free markets and lack of education in economics are two documented features of France. In this paper, we use data collected through an Internet-based survey conducted in December 2009 in order to test whether this situation is more than a mere coincidence.
Radu Vranceanu, Jérôme Barthélemy
openaire +3 more sources
The Application Of Local Indicators For Categorical Data (LICD) In The Spatial Analysis Of Economic Development [PDF]
, 2014 Firstly, we identify classes of regions presenting different economic development levels using taxonomic methods of multivariate data analysis. Secondly, we apply a join-count test to examine spatial dependencies between regions. It examines the tendency
Bivand, Roger S. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Patent Data in Economic Analysis
, 2017 The issues discussed in this chapter constitute a voice in a methodological discussion on the scope and manners of the utilisation of patent statistics in economic research. The discussion comprises the following issues: the gist of a patent monopoly, the evolution of opinions on the benefits and costs of a patent monopoly, and the possibilities and ...
openaire +4 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Examining the Relationship Among Economic Growth, Exports and Total Productivity for OECD Countries Using Data Envelopment Analysis and Panel Data Analyses [PDF]
Montenegrin Journal of Economics, 2017 The main objective of this paper is to explore the relationship between Total Factor Productivity (TFP) and economic growth and exports for OECD countries for the sample period 1990-2013.
İbrahim Hüseyni +2 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source