Results 161 to 170 of about 657,346 (266)

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

Caregiver distress explains links between objective and subjective socioeconomic status and adolescent internalizing and externalizing behaviors. [PDF]

J Fam Psychol
Miller P, Jones E, Parker H, Leverett-Ptak C, Hanson JL, Votruba-Drzal E.   +5 more
europepmc   +1 more source

Closed‐Loop Radiative Cooling Mulch Upcycled From Agricultural Residues for Efficient Soil Heat–Water Stress Mitigation

Advanced Science, EarlyView.
Conventional passive radiative cooling films rely on costly feedstocks and energy‐intensive fabrication, with poor end‐of‐life compatibility in agriculture. To address this challenge, a sustainable radiative cooling mulch (SRCM) is developed from waste maize leaves via spontaneous hydrogen‐bond self‐assembly.
Hao Li, Dong Lv, Yang Fu, Cancheng Jiang, Wenqi Wang, Ze Li, Lin Liang, Jiayu Du, Jie Tan, Yihao Zhu, Wenjie Liu, Lamfeddal Kouisni, Kaixin Lin, Chi Yan Tso   +13 more
wiley   +1 more source

Changes in the Education-Health Gradient Within U.S. States, 1993-2019. [PDF]

Popul Res Policy Rev
Montez JK, Gutin I, Finan JM, Zajacova A, Landes S.   +4 more
europepmc   +1 more source

Machine Learning‐Assisted KCl‐CaCl2‐LiCl Electrolyte Design for Low‐Temperature, High‐Performance Calcium‐Based Liquid Metal Batteries

Advanced Science, EarlyView.
A machine learning‐assisted framework optimizes the KCl‐CaCl2‐LiCl ternary electrolyte. The optimized 13:35:52 mol% composition enables Ca‐based liquid metal batteries to operate stably at 480 °C, with >99.5% coulombic efficiency, ultralow self‐discharge, and excellent cycling stability, advancing low‐temperature large‐scale energy storage.
Xinglin Zhou, Lei Huang, Yan Zhou, Xiaohui Ning   +3 more
wiley   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Exploring married women's economic dependency and family dynamics: a qualitative case study from Pakistan. [PDF]

Int J Qual Stud Health Well-being
Laar RA, Liu R, Zhang Q.
europepmc   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Resilience and Recovery in the Informal Economy: Social Networks, Social Protection, and Adaptive Strategies Among Post-COVID Workers in Bangladesh. [PDF]

Public Health Chall
Mamun MAA, Uddin KF, Uddin MS, Jahangir Kabir ANM, Sarker MNI.   +4 more
europepmc   +1 more source

Versatile Detection of Cellular Protein via Fluorescence Anisotropy

Advanced Science, EarlyView.
Cell Lysate Fluorescence Anisotropy (CFAST) utilizes long lifetime dye‐labeled nanobodies for rapid protein quantification in minimally purified, complex cell lysate. When coupled with cellular thermal shift, CFAST allows high‐throughput detection of endogenous protein‐small molecule engagement, facilitating the discovery of novel binders for ...
Qing Tang, Yuan‐Ping Wei, Ricky Ruiqi Ma, Na Wei, Tammy Zihan Zhou, Hilary Kung‐Yu Ho, Zafar Iqbal Bhat, Iqra Ishrat, Xiaoyu Li, Judy Wai Ping Yam, Yung Hou Wong, Qiankun Wang, Justin L. Tan   +12 more
wiley   +1 more source