Results 61 to 70 of about 11,526,139 (375)
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Vietnam's Economic History: The Feudalism System [PDF]
, 2011 We need a few words on the economic system and structure of the country before the sea change brought about by French colonialists could be fully appreciated in terms of economic performance and social context. Generally speaking, until early Xth century,
Vuong, Quan-Hoang
core
Essays in Economic and Business History, 2020 This article examines the liberalization of one of the oldest monopolies in Rhodesia, the Salisbury Municipality’s monopoly over the production and sale of African beer in the city from the 1960s to the early 1980s.
Nathaniel Chimhete, Eric Makombe
doaj
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
An economic history of Hundi, 1858-1978 [PDF]
, 2012 A centuries-old artery of credit for Indian merchant networks, the indigenous credit system hundi has received no systematic attention in histories of the Indian subcontinent.
Martin, Marina
core
The Role of Energy Quality in Shaping Long-Term Energy Intensity in Europe
Energies, 2014 On the European aggregate level there is an inverted-U curve for long-term energy intensity. In the 19th century aggregate European energy intensity rose, followed by a declining trend during the 20th century.
Ruta Gentvilaite +2 more
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
, 2008 Economic history focuses on the historical study of growth and development. Originating in the German historical school and studies of the Industrial Revolution in England, it became professionally differentiated from economics proper with the establishment of associations in Britain (1926) and the United States (1941).
openaire +2 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source