Results 71 to 80 of about 2,346,093 (382)
SOCIAL INTEGRATION OF MOLDOVAN MIGRANT’S CHILDREN IN ITALY
The article explores the features of the Moldovan migrant's children integration in Italy and the dynamics and particularities of the second-generation formation.
Ecaterina Deleu
doaj +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
CHANGES IN MORTALITY DURING THE COVID-19 PANDEMIC IN MOLDOVA
The study aims to highlight changes in mortality during the Covid-19 pandemic in Moldova. Two sources of data were used: the National Bureau of Statistics database for overall mortality and mortality by major and specific causes of death and the Ministry
Irina Pahomii
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source
An Analysis of Environmental Law in Pakistan-policy and Conditions of Implementation
We have human-environment relations inseparable since the creation of mankind. Being a developing country, Pakistan is striving to make developments in all the respective fields which alleviate our hot raising socio- economic issues.
M. Sohail+4 more
semanticscholar +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini+2 more
wiley +1 more source
Experiences of Capitalism in India and Pakistan [PDF]
The objective of this study is to examine the economic policies and socio-economic changes which have taken place in South Asia for the last six decades.
Siddiqui, Kalim
core +1 more source
Card games are effective tools to enhance foundation year health and safety inductions
A series of three card games was developed to actively deliver health and safety education to foundation year students. Most students reported positive responses regarding their enjoyment (89.9 %) and learning (74.7 %) from all games evaluated. Data revealed significant improvements in health and safety knowledge (P < 0.0001).
Rumana Rafiq+4 more
wiley +1 more source
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang+16 more
wiley +1 more source