Results 181 to 190 of about 403,672 (299)

Direct and indirect effects of economic sanctions on health: a systematic narrative literature review. [PDF]

BMC Public Health
Yazdi-Feyzabadi V, Zolfagharnasab A, Naghavi S, Behzadi A, Yousefi M, Bazyar M.   +5 more
europepmc   +1 more source

Optimal magnitude and probability of fines [PDF]

The economic literature on crime and punishment focuses on the trade-off between probability and severity of punishment, and suggests that detection probability and fines are substitutes.
Nuno Garoupa
core  

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Impacts of economic sanctions on population health and health system: a study at national and sub-national levels from 2000 to 2020 in Iran. [PDF]

Global Health
Mohamadi E, Kraemer A, Majdzadeh R, Mohamadzade M, Mohammadshahi M, Kiani MM, Ebrahimi F, Mostafavi H, Olyaeemanesh A, Takian A.   +9 more
europepmc   +1 more source

The scope of criminal law and criminal sanctions: An economic view and policy implications [PDF]

This paper considers why some harm-generating activities are controlled by criminal law and criminal sanctions while others are subject to some other mechanism such as civil law, administrative law, regulation or the tax system.
Michael Faure, Nuno Garoupa, Roger Bowles   +2 more
core  

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Re-evaluating the Conceptual Framework of Health System Resilience: Insights From Economic Sanctions Comment on "Re-evaluating Our Knowledge of Health System Resilience During COVID-19: Lessons From the First Two Years of the Pandemic". [PDF]

Int J Health Policy Manag
Sajadi HS, Majdzadeh R.
europepmc   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

The experiences and perceptions of people with chronic and rare diseases during political-economic sanctions in Iran: a qualitative study. [PDF]

BMC Health Serv Res
Kiani MM, Mostafavi H, Ebrahimi F, Majdzadeh R, Mohamadi E, Kraemer A, Olyaeemanesh A, Takian A.   +7 more
europepmc   +1 more source