β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Assessing the Ecological Value: Monetizing Process Innovations in Tailored Forming
Advanced Engineering Materials, EarlyView.This article introduces a method for evaluating the sustainability of innovations, even with limited data. The method is illustrated through an analysis of the “Tailored Forming” technology, which explores the impact of sustainability on economic value added.
Jonas Schneider +4 more
wiley +1 more source
Pathways for socio-economic system transitions expressed as a Markov chain. [PDF]
PLoS One, 2023 Schweizer VJ +4 more
europepmc +1 more source
Simulation of Inhomogeneous Refractive Index Fields Induced by Hot Tailored Forming Components
Advanced Engineering Materials, EarlyView.This article presents a simulation model for simulating inhomogeneous refractive index fields (IRIF) in hot‐forged components, accounting for thermal influences and complex geometries. Through this simulation, a priori knowledge about the propagation of the IRIF can be obtained, allowing for the positioning of the component or an optical measurement ...
Pascal Kern +3 more
wiley +1 more source
Dependence on the socio-economic system impairs the sustainability of pasture-based animal agriculture. [PDF]
Sci Rep, 2023 Muñoz-Ulecia E +4 more
europepmc +1 more source
A Novel Simulation Approach for Damage Evolution during Tailored Forming
Advanced Engineering Materials, EarlyView.Traditional damage models are struggling to accurately and efficiently simulate large‐scale three‐dimensional models with a great number of degrees of freedoms. A new gradient‐enhanced damage model based on the extended Hamilton principle can significantly reduce the computation time while ensuring mesh‐independence which is suitable to use in tailored
Fangrui Liu +2 more
wiley +1 more source
Social position and economic system justification in Canada: Implications for advancing health equity and social justice from an exploratory study of factors shaping economic system justification. [PDF]
Front Public Health, 2022 Card KG, Hepburn K.
europepmc +1 more source
Mechanisms of De‐icing by Surface Rayleigh and Plate Lamb Acoustic Waves
Advanced Engineering Materials, EarlyView.Ice accretion impacts daily life, renewable energy generation, maintenance, and security in industries and aeronautics. Acoustic waves (AW) are a promising method for ice removal, although de‐icing mechanisms require further investigation to optimize energy efficiency.
Shilpi Pandey +15 more
wiley +1 more source
Sustaining Livelihoods or Saving Lives? Economic System Justification in the Time of COVID-19. [PDF]
J Bus Ethics, 2023 Jain SS, Jain SP, Li YJ.
europepmc +1 more source