Results 41 to 50 of about 971,834 (238)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Research on a new power system development planning model based on two-tier planning

Frontiers in Energy Research
With the rapid development of the power industry, the safe and stable operation of the power system has become an important basis for safeguarding economic and social development.
Liu Fang, Xu Ke, Liu Yang, Xu Weiding, Ma Ruiguang, Ma Tiannan, Su Yunche, Liu Chang, Chen Wei   +8 more
doaj   +1 more source

INCREASING THE LEVEL OF INVESTMENT ATTRACTIVENESS OF THE REGION

Вестник Северо-Кавказского федерального университета, 2022
The article considers the role of investments in the economy of the region, determines that investments have a positive impact on the economic, social and other spheres of society, allow improving the attractiveness of the regions for foreign investors ...
M. Rybasova
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

National Security and Coronavirus Disease (COVID-19) Pandemic: Challenges to the Economic System of the State and Prospects for Ensuring its Security

Регионология, 2020
Introduction. The current transformation of economic relations in the society caused by coronavirus disease (COVID-19) pandemic poses a threat to national security of all countries.
Natalia S. Bezuglaya, Inna N. Shamray
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

DYNAMIC DEVELOPMENT OF THE RESIDENTIAL REAL ESTATE MARKET IN MOSCOW

Наука Красноярья
Moscow occupies a special place in the real estate market of the Russian Federation, as it is characterized by a large volume of new residential real estate, the existence of large market players and the presence of high (compared with other regions of ...
Yulia A. Milkina, Ekaterina E. Makarova
doaj   +1 more source

INTEGRATION OF A CLUSTER AND A SPECIAL ECONOMIC ZONE AS A TOOL FOR IMPROVING THE EFFICIENCY OF REGIONAL ECONOMIC SYSTEMS

Вестник университета, 2020
Industrial clusters and special economic zones, which are forms of regional development tools, have been considered. Within the framework of research clusters and special economic zones according to a number of criteria have been compared, measures of ...
O. D. Gaisha
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source