Results 61 to 70 of about 754,306 (314)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Research on the Shadow Economy and Assessment of Its Scale: On the Example of Kazakhstan

Economies
The manuscript aims to assess the scale of shadow economic processes within the non-observed economy, focusing on the self-employment sector, which is insufficiently reflected in national statistics.
Aziza Mergenbayeva, Kulyanda Nurasheva, Aizhan Abishova, Gulnara Urazbayeva   +3 more
doaj   +1 more source

Comparative characteristics of world agricultural markets using contracting and state farm support development (Russian Agribusiness Case Study)

BIO Web of Conferences, 2020
Theoretical and methodological aspects of direct and indirect methods of farm regulation are being discussed. One of the most important goals is regulation of the agro-industrial complex.
Zhichkin Kirill, Penkin Anatoly, Balashenko Vyacheslav, Zhichkina Lyudmila   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The structure of authority, federalism, commitment and economic growth [PDF]

, 2009
In a neoclassical growth model with many regions and a mobile factor, two federal arrangements are considered. In the first federal arrangement the central government chooses a uniform tax policy, whereas in the second each regional government chooses ...
Ronald Edwards, 艾德榮; Ronald Alan Edwards   +1 more
core   +1 more source

Environmental Welfare: Quality of Policy vs. Society’s Values

Problemy Ekorozwoju, 2019
In the 21st century, in addition to the generally well-known indicators of material well-being, in the modern paradigm of the welfare state, the quality of the ecological environment is gaining an ever-increasing role.
Oleksandr Dluhopolskyi, Victor Koziuk, Yuryi Ivashuk, Yuryi Klapkiv   +3 more
doaj  

ENTREPRENEURIAL STRATEGIES IN THE FOOD INDUSTRY: CONSUMER INFLUENCE, DIGITAL PLATFORM OPPORTUNITIES, AND OVERCOMING REGULATORY CHALLENGES

Менеджмент та підприємництво в Україні: етапи становлення і проблеми розвитку
his article explores entrepreneurial strategies in the food industry, highlighting the growing role of digital platforms, social media, and innovative technologies in shaping consumer behavior and business development.
Shyshliuk V., Zabolotna O
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Contours of New Economic Theory [PDF]

, 2015
The need for a paradigm change in economic thought has been well established, but the contours and fundamental characteristics of a new paradigm in economic theory are yet to be worked out.
Garry Jacobs
core